ARHGDIB

Name	Rho GDP dissociation inhibitor beta
Structure
Interactors	14 interactors: ANKRD1 APP CASP3 CDC42 CEBPA EZR RAC1 RAC2 RAC3 RHOA RHOH UBE3A UFM1 VAV1
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Membrane Cytoplasmic Vesicle Extracellular Exosome
	Molecular Function	GTPase Activity Rho GDP-dissociation Inhibitor Activity GTPase Activator Activity Protein Binding Small GTPase Binding
	Biological Process	Rho Protein Signal Transduction Regulation Of Rho Protein Signal Transduction Cellular Response To Redox State Negative Regulation Of Trophoblast Cell Migration
Pathways	RHOA GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle RHOH GTPase cycle RHOG GTPase cycle RAC3 GTPase cycle
GWAS	No GWAS studies recorded
Entrez ID	397
HPRD ID	04162
Ensembl ID	ENSG00000111348
Uniprot IDs	P52566
PDB IDs	1DS6 5H1D
GO Terms Enriched among Interactors ?	Intracellular Signal Transduction Intracellular Signaling Cassette Actin Filament Organization Small GTPase-mediated Signal Transduction Supramolecular Fiber Organization Establishment Or Maintenance Of Cell Polarity Actin Cytoskeleton Organization Actin Filament-based Process Regulation Of Immune System Process Cortical Cytoskeleton Organization Regulation Of Cell Adhesion GTPase Activity Chemotaxis Signal Transduction Regulation Of Actin Cytoskeleton Organization Locomotion GTP Binding Regulation Of Plasma Membrane Bounded Cell Projection Organization Regulation Of Cell Activation Regulation Of Intracellular Signal Transduction G Protein Activity Regulation Of Actin Filament-based Process Establishment Of Epithelial Cell Apical/basal Polarity NADPH Oxidase Complex Regulation Of Cell Projection Organization Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Regulation Of Cell-substrate Adhesion Respiratory Burst Cerebral Cortex GABAergic Interneuron Development Cellular Developmental Process Establishment Of Apical/basal Cell Polarity Regulation Of Leukocyte Migration Postsynapse Endocytosis Polarized Epithelial Cell Differentiation Protein Kinase Binding Establishment Of Monopolar Cell Polarity Establishment Or Maintenance Of Monopolar Cell Polarity Cell Periphery Positive Regulation Of Lamellipodium Assembly Positive Regulation Of Protein Metabolic Process Developmental Process Positive Regulation Of Cell Adhesion Establishment Of Epithelial Cell Polarity Regulation Of Cytoskeleton Organization Wnt Signaling Pathway, Planar Cell Polarity Pathway Regulation Of Vesicle-mediated Transport Response To Cytokine Positive Regulation Of Lamellipodium Organization Regulation Of Synapse Organization