MYL7 and PSORS1C2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MYL7	PSORS1C2
Description		myosin light chain 7	psoriasis susceptibility 1 candidate 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Myosin Complex Myofibril A Band Dendritic Spine	Extracellular Region
	Molecular Function	Calcium Ion Binding Protein Binding Metal Ion Binding	Protein Binding
	Biological Process	Cardiac Muscle Tissue Development Heart Contraction
Pathways		Smooth Muscle Contraction
Drugs
Diseases
GWAS		Fasting blood glucose ( 33842983) Offspring birth weight ( 31043758) Type 2 diabetes ( 32499647)	Asthma ( 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Broad depression or schizophrenia ( 30626913) Clostridioides difficle infection in antibiotics-users ( 33841421) Height ( 25282103 28552196) Hematology traits ( 23263863) Hip circumference adjusted for BMI ( 34021172) Inflammatory bowel disease ( 28067908) Malaria ( 31844061) Metabolite levels ( 23823483) Multiple myeloma ( 26007630 33875642) Multiple myeloma and monoclonal gammopathy ( 26007630) Night sleep phenotypes ( 27126917) Serum uric acid levels ( 30993211) Ulcerative colitis ( 28067908) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172) White blood cell count ( 21738480)
Interacting Genes		7 interacting genes: MCCD1 MEOX2 POU6F2 PPM1B PSORS1C2 SUOX TOX4	27 interacting genes: AGR2 AP1B1 AP2B1 BANP CEP70 ERICH2 EVPL GUCA1C HMG20A HOMER3 LHX3 MED20 MEIS3 MYL2 MYL7 NCKIPSD PAX6 PEX19 REL RTRAF SERTAD1 SGTA SGTB TTC23 UBQLN1 UBQLN2 VASP
Entrez ID		58498	170680
HPRD ID		10105	17921
Ensembl ID		ENSG00000106631	ENSG00000204538
Uniprot IDs		Q01449	A0A1U9X9A6 Q9UIG4
PDB IDs
Enriched GO Terms of Interacting Partners?			Positive Regulation Of Response To Endoplasmic Reticulum Stress TRC Complex Positive Regulation Of ERAD Pathway Regulation Of ERAD Pathway Regulation Of Response To Endoplasmic Reticulum Stress Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Clathrin Adaptor Complex A Band Cell Fate Specification Protein Targeting Identical Protein Binding ERAD Pathway Response To Endoplasmic Reticulum Stress Heart Contraction Positive Regulation Of Proteasomal Protein Catabolic Process Clathrin Binding Membrane Coat Heart Process Muscle Cell Fate Specification Forebrain-midbrain Boundary Formation Pituitary Gland Development Pancreatic A Cell Development Negative Regulation Of Lipid Binding Peroxisome Membrane Class-1 Targeting Sequence Binding Establishment Of Protein Localization To Endoplasmic Reticulum Protein Targeting To ER Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Negative Regulation Of Store-operated Calcium Channel Activity
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