PSORS1C2 and ERICH2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PSORS1C2	ERICH2
Description		psoriasis susceptibility 1 candidate 2	glutamate rich 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region
	Molecular Function	Protein Binding	Protein Binding
	Biological Process
Pathways
Drugs
Diseases
GWAS		Asthma ( 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Broad depression or schizophrenia ( 30626913) Clostridioides difficle infection in antibiotics-users ( 33841421) Height ( 25282103 28552196) Hematology traits ( 23263863) Hip circumference adjusted for BMI ( 34021172) Inflammatory bowel disease ( 28067908) Malaria ( 31844061) Metabolite levels ( 23823483) Multiple myeloma ( 26007630 33875642) Multiple myeloma and monoclonal gammopathy ( 26007630) Night sleep phenotypes ( 27126917) Serum uric acid levels ( 30993211) Ulcerative colitis ( 28067908) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172) White blood cell count ( 21738480)	Metabolic syndrome ( 31589552) Triglyceride levels ( 32203549)
Interacting Genes		27 interacting genes: AGR2 AP1B1 AP2B1 BANP CEP70 ERICH2 EVPL GUCA1C HMG20A HOMER3 LHX3 MED20 MEIS3 MYL2 MYL7 NCKIPSD PAX6 PEX19 REL RTRAF SERTAD1 SGTA SGTB TTC23 UBQLN1 UBQLN2 VASP	5 interacting genes: FBXO7 IWS1 MACROH2A1 PSORS1C2 SDCBP
Entrez ID		170680	285141
HPRD ID		17921
Ensembl ID		ENSG00000204538	ENSG00000204334
Uniprot IDs		A0A1U9X9A6 Q9UIG4	A0A8V8TMA0 A0A8V8TMB5 A1L162
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Response To Endoplasmic Reticulum Stress TRC Complex Positive Regulation Of ERAD Pathway Regulation Of ERAD Pathway Regulation Of Response To Endoplasmic Reticulum Stress Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Clathrin Adaptor Complex A Band Cell Fate Specification Protein Targeting Identical Protein Binding ERAD Pathway Response To Endoplasmic Reticulum Stress Heart Contraction Positive Regulation Of Proteasomal Protein Catabolic Process Clathrin Binding Membrane Coat Heart Process Muscle Cell Fate Specification Forebrain-midbrain Boundary Formation Pituitary Gland Development Pancreatic A Cell Development Negative Regulation Of Lipid Binding Peroxisome Membrane Class-1 Targeting Sequence Binding Establishment Of Protein Localization To Endoplasmic Reticulum Protein Targeting To ER Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Negative Regulation Of Store-operated Calcium Channel Activity	Interleukin-5 Receptor Complex Protein Heterodimerization Activity Negative Regulation Of Protein Localization To Chromosome, Telomeric Region Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite Interleukin-5 Receptor Binding ADP-D-ribose Binding Regulation Of NAD Metabolic Process Regulation Of RDNA Heterochromatin Formation Positive Regulation Of Endodermal Cell Differentiation Positive Regulation Of Response To Oxidative Stress ADP-D-ribose Modification-dependent Protein Binding Lewy Body Core Positive Regulation Of Extracellular Exosome Assembly Syndecan Binding Negative Regulation Of Transcription Of Nucleolar Large RRNA By RNA Polymerase I Protein Targeting Regulation Of Extracellular Exosome Assembly Poly-ADP-D-ribose Modification-dependent Protein Binding RDNA Binding Sex Chromatin Negative Regulation Of Cell Cycle Phase Transition Positive Regulation Of Maintenance Of Mitotic Sister Chromatid Cohesion Double-stranded Methylated DNA Binding Barr Body Transcription Elongation-coupled Chromatin Remodeling Regulation Of Cell Cycle Negative Regulation Of Cell Cycle Process Negative Regulation Of Response To Oxidative Stress Establishment Of Protein Localization To Chromatin Regulation Of Heterochromatin Formation Substrate-dependent Cell Migration, Cell Extension Negative Regulation Of Transcription By RNA Polymerase I Positive Regulation Of Sister Chromatid Cohesion Regulation Of MRNA Export From Nucleus Establishment Of Protein Localization Establishment Of Protein Localization To Organelle Regulation Of Transcription Of Nucleolar Large RRNA By RNA Polymerase I Negative Regulation Of Cell Cycle Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Exosomal Secretion Negative Regulation Of Receptor Internalization Regulation Of Sister Chromatid Cohesion Protein Poly-ADP-ribosylation Regulation Of RNA Export From Nucleus Regulation Of Exosomal Secretion Positive Regulation Of Keratinocyte Differentiation Cytoskeletal Anchor Activity
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