RSPO4 and ZNF330

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RSPO4	ZNF330
Description		R-spondin 4	zinc finger protein 330
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Chromosome, Centromeric Region Nucleus Nucleoplasm Chromosome Nucleolus Cytosol Cilium Midbody Ciliary Basal Body
	Molecular Function	Signaling Receptor Binding Protein Binding Heparin Binding	Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Wnt Signaling Pathway Positive Regulation Of Wnt Signaling Pathway Nail Development Limb Development Positive Regulation Of Canonical Wnt Signaling Pathway
Pathways		Regulation of FZD by ubiquitination
Drugs
Diseases		Anonychia congenita
GWAS		Blood protein levels ( 30072576) Lean body mass ( 28552196) Logical memory (immediate recall) in Alzheimer's disease dementia ( 29274321)	Conduct disorder ( 20585324) Malaria ( 31844061)
Interacting Genes		15 interacting genes: ANKRD11 DHX57 GNG13 GPSM3 GUCD1 HGS KLHL38 LGR4 MAPK9 MKRN3 PIH1D2 STK16 USP20 ZNF330 ZNF77	51 interacting genes: ADAMTSL4 CCDC33 CCN3 CFP CHIC2 CNNM3 CREB5 CYSRT1 KLF15 KRTAP1-1 KRTAP1-3 KRTAP10-8 KRTAP13-3 KRTAP5-7 MDFI MEOX2 NBPF19 NDUFB7 NOTCH2NLA NR4A3 OTX1 PBX4 PICK1 RBAK RSPO2 RSPO4 SPATA3 SPRY1 STK16 STX19 SUFU TCL1B TLE5 TRIM42 ZBTB42 ZNF23 ZNF250 ZNF408 ZNF426 ZNF440 ZNF460 ZNF547 ZNF587 ZNF655 ZNF664 ZNF669 ZNF683 ZNF688 ZNF764 ZNF768 ZNF837
Entrez ID		343637	27309
HPRD ID		18788	15775
Ensembl ID		ENSG00000101282	ENSG00000109445
Uniprot IDs		Q2I0M5	B4DFG9 Q53EN0 Q9Y3S2
PDB IDs
Enriched GO Terms of Interacting Partners?			DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process DNA Binding Zinc Ion Binding Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Metal Ion Binding Intermediate Filament Sequence-specific Double-stranded DNA Binding Protein Binding Regulation Of Macromolecule Metabolic Process Limb Development CAMP Response Element Binding DNA-binding Transcription Factor Activity Golgi-associated Vesicle
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