SLAMF7 and THRSP

		SLAMF7	THRSP
Description		SLAM family member 7	thyroid hormone responsive
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane External Side Of Plasma Membrane Membrane	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Identical Protein Binding	Protein Binding Identical Protein Binding Protein Homodimerization Activity Molecular Function Inhibitor Activity
	Biological Process	Adaptive Immune Response Immune System Process Immune Response Cell Adhesion Natural Killer Cell Activation T Cell Activation Natural Killer Cell Mediated Cytotoxicity Innate Immune Response	Lipid Metabolic Process Response To Bacterium Regulation Of Triglyceride Biosynthetic Process Regulation Of Lipid Biosynthetic Process
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	Carnitine shuttle MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
Drugs		Elotuzumab
Diseases
GWAS		Blood protein levels ( 30072576) IgM levels ( 28628107) Inflammatory bowel disease ( 23128233) Microalbuminuria ( 26631737) Multiple sclerosis ( 24076602)	Menarche (age at onset) ( 25231870) Tourette syndrome ( 30818990)
Interacting Genes		4 interacting genes: CLK3 MAK SH2D1A TRIB2	25 interacting genes: AKT1 AURKA BAG4 BCAR3 BRMS1 ERBB2 FGFR4 FZR1 HMMR IGF1R INCA1 KRAS LSP1 PALB2 PARP1 PIK3CA PTPN1 RB1CC1 SMAD4 STK11 TEPSIN TGFB1 TSG101 WT1 ZMYND12
Entrez ID		57823	7069
HPRD ID		09432	03566
Ensembl ID		ENSG00000026751	ENSG00000151365
Uniprot IDs		B4DVL7 B4DW98 Q9NQ25	Q92748
PDB IDs
Enriched GO Terms of Interacting Partners?		Cytoplasm Negative Regulation Of Uterine Smooth Muscle Contraction Alpha-1B Adrenergic Receptor Binding Alpha-2C Adrenergic Receptor Binding Phospholipase C-activating Adrenergic Receptor Signaling Pathway Protein Homodimerization Activity Adenylate Cyclase-inhibiting Adrenergic Receptor Signaling Pathway Protein Phosphorylation Negative Regulation Of Non-motile Cilium Assembly Skeletal Muscle Tissue Development Left Lung Morphogenesis Superior Vena Cava Morphogenesis Prolactin Secreting Cell Differentiation Cell Proliferation Involved In Outflow Tract Morphogenesis Pulmonary Vein Morphogenesis Subthalamic Nucleus Development Regulation Of Actin Filament Depolymerization Actin Filament Capping Negative Regulation Of Protein-containing Complex Disassembly Negative Regulation Of Actin Filament Depolymerization Negative Regulation Of Actin Filament Polymerization Pantothenate Kinase Activity Regulation Of Protein Depolymerization Actin Filament-based Process Alpha2-adrenergic Receptor Activity Phosphorylation Pulmonary Myocardium Development Endodermal Digestive Tract Morphogenesis Deltoid Tuberosity Development Norepinephrine Binding Thermoception Somatotropin Secreting Cell Differentiation Cell Proliferation Involved In Heart Morphogenesis Acetyl-CoA Binding Negative Regulation Of Norepinephrine Secretion Epinephrine Binding Negative Regulation Of Epinephrine Secretion Protein Kinase Activity Striated Muscle Tissue Development Embryonic Heart Tube Left/right Pattern Formation Muscle Structure Development Extraocular Skeletal Muscle Development Atrioventricular Valve Development Regulation Of Actin Filament Polymerization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Regulation Of Protein-containing Complex Disassembly Negative Regulation Of Protein-containing Complex Assembly Ubiquitin-protein Transferase Regulator Activity Pointed-end Actin Filament Capping	Regulation Of Apoptotic Process Regulation Of Programmed Cell Death Regulation Of Cell Population Proliferation Positive Regulation Of Signal Transduction Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Cell Communication Positive Regulation Of Signaling Regulation Of Signal Transduction Enzyme-linked Receptor Protein Signaling Pathway Carbohydrate Homeostasis Glucose Homeostasis Negative Regulation Of Apoptotic Process Regulation Of Intracellular Signal Transduction Negative Regulation Of Programmed Cell Death Regulation Of Protein Metabolic Process Regulation Of Catalytic Activity Regulation Of Cell Communication Regulation Of Signaling Insulin Receptor Signaling Pathway Gland Development Cellular Response To Growth Factor Stimulus Apoptotic Process Response To Growth Factor Regulation Of Cellular Component Organization Positive Regulation Of Cell Population Proliferation Liver Development Programmed Cell Death Cell Death Anoikis Negative Regulation Of Cell Population Proliferation Protein-containing Complex Binding Protein Autophosphorylation Cell Surface Receptor Signaling Pathway Epithelial Cell Differentiation Regulation Of Cell Growth Positive Regulation Of Fibroblast Migration Regulation Of Growth Epidermal Growth Factor Receptor Signaling Pathway Cellular Response To Glucose Stimulus Regulation Of Protein Modification Process Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of MAPK Cascade Positive Regulation Of MAPK Cascade Regulation Of Protein Localization Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Cellular Response To Carbohydrate Stimulus ERBB Signaling Pathway Cellular Response To Peptide Hormone Stimulus Positive Regulation Of Catalytic Activity Cell Population Proliferation
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