SLAMF7 and TRIB2

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		SLAMF7	TRIB2
Gene Name		SLAM family member 7	tribbles pseudokinase 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Membrane	Cytoplasm Cytoskeleton
	Molecular Function	Receptor Activity	Nucleotide Binding Protein Kinase Activity Protein Kinase Inhibitor Activity Transcription Factor Binding Ubiquitin Protein Ligase Binding Ubiquitin-protein Transferase Regulator Activity
	Biological Process	Cell Adhesion Natural Killer Cell Activation Natural Killer Cell Mediated Cytotoxicity	Protein Phosphorylation Negative Regulation Of Protein Kinase Activity Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of MAP Kinase Activity Negative Regulation Of Interleukin-10 Biosynthetic Process Negative Regulation Of Fat Cell Differentiation
Pathways
Drugs
Diseases
GWAS		Inflammatory bowel disease ( 23128233)	Dental caries ( 23064961) Pericardial fat ( 22589742)
Protein-Protein Interactions		4 interactors: CLK3 MAK SH2D1A TRIB2	4 interactors: APP PRMT6 SLAMF7 UBQLN4
Entrez ID		57823	28951
HPRD ID		09432	18224
Ensembl ID		ENSG00000026751	ENSG00000071575
Uniprot IDs		Q9NQ25	Q92519
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Interleukin-10 Biosynthetic Process Protein Autophosphorylation Protein Phosphorylation	Histone H3-R2 Methylation Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition
Tagcloud ?		antibody autoimmunity biology cd319 compelling cracc cs1 discusses elotuzumab expressed family focuses hematopoietic humanized immunity immunodeficiencies implicated knowledge lymphocytic member mm molecule monoclonal myeloma nearly normal preclinical universally	aberrantly activates autoregulatory circuit circuitry core downstream e2a emphasizing feed forming forward gata3 heb interconnected lmo1 loop lymphoblastic myb oncogene oncogenic oppositely partners program regulatory reinforces runx1 stabilizes tal1
Tagcloud (Difference) ?		antibody autoimmunity biology cd319 compelling cracc cs1 discusses elotuzumab expressed family focuses hematopoietic humanized immunity immunodeficiencies implicated knowledge lymphocytic member mm molecule monoclonal myeloma nearly normal preclinical universally	aberrantly activates autoregulatory circuit circuitry core downstream e2a emphasizing feed forming forward gata3 heb interconnected lmo1 loop lymphoblastic myb oncogene oncogenic oppositely partners program regulatory reinforces runx1 stabilizes tal1
Tagcloud (Intersection) ?