ANO8 and COQ9

Number of citations: 0 (PubMedID 16169070)
Data Source: HPRD (two hybrid)

		ANO8	COQ9
Name		anoctamin 8	coenzyme Q9
Structure		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Lumen Plasma Membrane Membrane	Mitochondrion Mitochondrial Inner Membrane Ubiquinone Biosynthesis Complex
	Molecular Function	Intracellularly Calcium-gated Chloride Channel Activity Chloride Channel Activity	Protein Binding Enzyme Activator Activity Lipid Binding Isoprenoid Binding Protein Homodimerization Activity
	Biological Process	Monoatomic Ion Transmembrane Transport Chloride Transmembrane Transport	Mitochondrial Electron Transport, NADH To Ubiquinone Ubiquinone Biosynthetic Process
Pathways		Stimuli-sensing channels Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation Induction of Cell-Cell Fusion	Ubiquinol biosynthesis
Diseases		None	Coenzyme Q10 deficiency
GWAS		Major depressive disorder ( 27777418 ) Mitochondrial DNA copy number ( 30704525 ) Refractive error ( 32231278 )	No GWAS studies recorded
Interacting Genes		2 interacting genes: ADRA1A COQ9	33 interacting genes: ACSF2 ACTL6B ADIPOQ ALDH18A1 ANO8 BMP10 CCL4L2 CLNK COQ4 COQ8A CTSA CTXN3 CYB561D2 CYBC1 EHHADH GALNT2 HMOX1 KIR2DL3 MGLL ORMDL1 PLSCR2 SCARF1 SLC13A1 STX3 TEX264 TMEM14C TMEM79 TMEM86A TNFRSF10C TRAF3IP3 TSPAN33 VSTM1 WFDC2
Entrez ID		57719	57017
HPRD ID		17223	13157
Ensembl ID		ENSG00000074855	ENSG00000088682
Uniprot IDs		Q9HCE9	O75208
PDB IDs		Not available	4RHP 6AWL 6DEW 7SSP 7SSS
GO Terms Enriched among Interactors		Negative Regulation Of Heart Rate Involved In Baroreceptor Response To Increased Systemic Arterial Blood Pressure Positive Regulation Of The Force Of Heart Contraction By Epinephrine-norepinephrine Pilomotor Reflex Positive Regulation Of Heart Rate By Epinephrine-norepinephrine Alpha1-adrenergic Receptor Activity Phospholipase C-activating Adrenergic Receptor Signaling Pathway Norepinephrine-epinephrine Vasoconstriction Involved In Regulation Of Systemic Arterial Blood Pressure Positive Regulation Of The Force Of Heart Contraction By Chemical Signal Isoprenoid Binding Neuron-glial Cell Signaling Regulation Of The Force Of Heart Contraction By Chemical Signal Positive Regulation Of Cardiac Muscle Contraction Cell Growth Involved In Cardiac Muscle Cell Development Positive Regulation Of Action Potential Adrenergic Receptor Activity Ubiquinone Biosynthesis Complex Positive Regulation Of Striated Muscle Contraction Adult Heart Development Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Negative Regulation Of Heart Rate Ubiquinone Biosynthetic Process Positive Regulation Of Synaptic Transmission, GABAergic Ubiquinone Metabolic Process Reflex Quinone Metabolic Process Negative Regulation Of Heart Contraction Adrenergic Receptor Signaling Pathway Negative Regulation Of Blood Circulation Regulation Of The Force Of Heart Contraction Positive Regulation Of Heart Rate Positive Regulation Of Vasoconstriction Positive Regulation Of Smooth Muscle Contraction Vasoconstriction Ketone Biosynthetic Process Regulation Of Synaptic Transmission, GABAergic Positive Regulation Of Cardiac Muscle Hypertrophy Positive Regulation Of Heart Contraction Mitochondrial Electron Transport, NADH To Ubiquinone Organ Growth Positive Regulation Of Muscle Contraction Smooth Muscle Contraction Regulation Of Action Potential Regulation Of Smooth Muscle Contraction Regulation Of Vasoconstriction Caveola Regulation Of Cardiac Muscle Hypertrophy Aerobic Electron Transport Chain Enzyme Activator Activity Regulation Of Cardiac Muscle Contraction Ketone Metabolic Process	None