COQ9 and ACSF2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		COQ9	ACSF2
Description		coenzyme Q9	acyl-CoA synthetase family member 2
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Ubiquinone Biosynthesis Complex	Mitochondrion Mitochondrial Matrix
	Molecular Function	Protein Binding Enzyme Activator Activity Lipid Binding Isoprenoid Binding Protein Homodimerization Activity	Nucleotide Binding Catalytic Activity Long-chain Fatty Acid-CoA Ligase Activity Protein Binding ATP Binding Ligase Activity Medium-chain Fatty Acid-CoA Ligase Activity
	Biological Process	Mitochondrial Electron Transport, NADH To Ubiquinone Ubiquinone Biosynthetic Process	Long-chain Fatty Acid Metabolic Process Lipid Metabolic Process Fatty Acid Metabolic Process Acyl-CoA Metabolic Process
Pathways		Ubiquinol biosynthesis	Mitochondrial Fatty Acid Beta-Oxidation
Drugs
Diseases		Coenzyme Q10 deficiency
GWAS			Heel bone mineral density ( 30598549)
Interacting Genes		33 interacting genes: ACSF2 ACTL6B ADIPOQ ALDH18A1 ANO8 BMP10 CCL4L2 CLNK COQ4 COQ8A CTSA CTXN3 CYB561D2 CYBC1 EHHADH GALNT2 HMOX1 KIR2DL3 MGLL ORMDL1 PLSCR2 SCARF1 SLC13A1 STX3 TEX264 TMEM14C TMEM79 TMEM86A TNFRSF10C TRAF3IP3 TSPAN33 VSTM1 WFDC2	19 interacting genes: AGTRAP APOA5 APOC1 ARL13B ARL6IP1 C10orf67 CLEC10A CMTM5 COQ9 CREB3 DGAT2L6 GPR152 MICOS13 RDH10 RHBDD2 SENP2 SIGLEC12 SYNGR3 USP40
Entrez ID		57017	80221
HPRD ID		13157	13380
Ensembl ID		ENSG00000088682	ENSG00000167107
Uniprot IDs		O75208	B4DTB9 E9PF16 Q96CM8
PDB IDs		4RHP 6AWL 6DEW 7SSP 7SSS
Enriched GO Terms of Interacting Partners?			Phosphatidylcholine-sterol O-acyltransferase Activator Activity Very-low-density Lipoprotein Particle Clearance Acylglycerol Metabolic Process Chylomicron Neutral Lipid Metabolic Process Phospholipid Efflux Very-low-density Lipoprotein Particle High-density Lipoprotein Particle Regulation Of Ketone Metabolic Process Plasma Lipoprotein Particle Clearance Acylglycerol Homeostasis Protein-containing Complex Remodeling Lipoprotein Metabolic Process Phosphatidylcholine Binding Cholesterol Efflux Triglyceride Homeostasis Regulation Of Triglyceride Metabolic Process Plasma Lipoprotein Particle Remodeling Negative Regulation Of Phosphatidylcholine Catabolic Process Endoplasmic Reticulum Membrane Positive Regulation Of Deacetylase Activity Isoprenoid Binding Primary Lung Bud Formation Positive Regulation Of Retinoic Acid Biosynthetic Process Regulation Of Lipid Biosynthetic Process Regulation Of Fatty Acid Biosynthetic Process Regulation Of Lipid Catabolic Process Triglyceride Metabolic Process Positive Regulation Of Very-low-density Lipoprotein Particle Remodeling Lipase Activator Activity Endoplasmic Reticulum Unfolded Protein Response Cholesterol Transport Regulation Of Phosphatidylcholine Catabolic Process Membrane Lipoprotein Particle Receptor Binding Lipoprotein Lipase Activator Activity Receptor Localization To Non-motile Cilium Acylglycerol Acyl-chain Remodeling Sterol Transport Alcohol Metabolic Process
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