ANO8

Description		anoctamin 8
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Lumen Plasma Membrane Membrane
	Molecular Function	Intracellularly Calcium-gated Chloride Channel Activity Chloride Channel Activity
	Biological Process	Monoatomic Ion Transmembrane Transport Chloride Transmembrane Transport
Pathways		Stimuli-sensing channels Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation Induction of Cell-Cell Fusion
Drugs
Diseases
GWAS		Major depressive disorder ( 27777418) Mitochondrial DNA copy number ( 30704525) Refractive error ( 32231278)
Interacting Genes		2 interacting genes: ADRA1A COQ9
Entrez ID		57719
HPRD ID		17223
Ensembl ID		ENSG00000074855
Uniprot IDs		Q9HCE9
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Heart Rate Involved In Baroreceptor Response To Increased Systemic Arterial Blood Pressure Positive Regulation Of The Force Of Heart Contraction By Epinephrine-norepinephrine Pilomotor Reflex Positive Regulation Of Heart Rate By Epinephrine-norepinephrine Alpha1-adrenergic Receptor Activity Phospholipase C-activating Adrenergic Receptor Signaling Pathway Norepinephrine-epinephrine Vasoconstriction Involved In Regulation Of Systemic Arterial Blood Pressure Positive Regulation Of The Force Of Heart Contraction By Chemical Signal Isoprenoid Binding Neuron-glial Cell Signaling Regulation Of The Force Of Heart Contraction By Chemical Signal Positive Regulation Of Cardiac Muscle Contraction Cell Growth Involved In Cardiac Muscle Cell Development Positive Regulation Of Action Potential Adrenergic Receptor Activity Ubiquinone Biosynthesis Complex Positive Regulation Of Striated Muscle Contraction Adult Heart Development Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Negative Regulation Of Heart Rate Ubiquinone Biosynthetic Process Positive Regulation Of Synaptic Transmission, GABAergic Ubiquinone Metabolic Process Reflex Quinone Metabolic Process Negative Regulation Of Heart Contraction Adrenergic Receptor Signaling Pathway Negative Regulation Of Blood Circulation Regulation Of The Force Of Heart Contraction Positive Regulation Of Heart Rate Positive Regulation Of Vasoconstriction Positive Regulation Of Smooth Muscle Contraction Vasoconstriction Ketone Biosynthetic Process Regulation Of Synaptic Transmission, GABAergic Positive Regulation Of Cardiac Muscle Hypertrophy Positive Regulation Of Heart Contraction Mitochondrial Electron Transport, NADH To Ubiquinone Organ Growth Positive Regulation Of Muscle Contraction Smooth Muscle Contraction Regulation Of Action Potential Regulation Of Smooth Muscle Contraction Regulation Of Vasoconstriction Caveola Regulation Of Cardiac Muscle Hypertrophy Aerobic Electron Transport Chain Enzyme Activator Activity Regulation Of Cardiac Muscle Contraction Ketone Metabolic Process
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