PHRF1 and AGPAT2

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		PHRF1	AGPAT2
Gene Name		PHD and ring finger domains 1	1-acylglycerol-3-phosphate O-acyltransferase 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Membrane	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Zinc Ion Binding Protein Domain Specific Binding RNA Polymerase Binding	1-acylglycerol-3-phosphate O-acyltransferase Activity
	Biological Process	Transcription From RNA Polymerase II Promoter MRNA Processing	Positive Regulation Of Cytokine Production Positive Regulation Of Cytokine-mediated Signaling Pathway Phospholipid Metabolic Process Phosphatidic Acid Biosynthetic Process Epidermis Development CDP-diacylglycerol Biosynthetic Process Triglyceride Biosynthetic Process Cellular Lipid Metabolic Process Small Molecule Metabolic Process Glycerophospholipid Biosynthetic Process
Pathways			Synthesis of PA Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Phospholipid metabolism Glycerophospholipid biosynthesis Triglyceride Biosynthesis
Drugs
Diseases
GWAS
Protein-Protein Interactions		2 interactors: AGPAT2 CSNK2B	6 interactors: ABCG8 ANKRD28 GMPS PHF11 PHRF1 SLC23A2
Entrez ID		57661	10555
HPRD ID		13870	04373
Ensembl ID		ENSG00000070047	ENSG00000169692
Uniprot IDs		E9PJ24 F8WEF5 Q9P1Y6	O15120
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Activin Receptor Signaling Pathway Adiponectin-activated Signaling Pathway Endothelial Tube Morphogenesis CDP-diacylglycerol Biosynthetic Process CDP-diacylglycerol Metabolic Process Negative Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Activin Receptor Signaling Pathway Phosphatidic Acid Biosynthetic Process Phosphatidic Acid Metabolic Process Epithelium Development Positive Regulation Of Cytokine-mediated Signaling Pathway Positive Regulation Of Response To Cytokine Stimulus Positive Regulation Of Signal Transduction Negative Regulation Of Endothelial Cell Migration Triglyceride Biosynthetic Process Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Epithelial Cell Migration Regulation Of Pathway-restricted SMAD Protein Phosphorylation Tissue Development Regulation Of DNA Binding Endothelium Development Triglyceride Metabolic Process Regulation Of Cytokine-mediated Signaling Pathway Regulation Of Endothelial Cell Migration Neutral Lipid Metabolic Process	Negative Regulation Of Intestinal Phytosterol Absorption Negative Regulation Of Intestinal Cholesterol Absorption Transepithelial L-ascorbic Acid Transport Molecular Hydrogen Transport L-ascorbic Acid Transport GMP Biosynthetic Process Nucleobase Transport Intestinal Cholesterol Absorption GMP Metabolic Process Regulation Of Intestinal Cholesterol Absorption Negative Regulation Of Cholesterol Transport Lipid Digestion L-ascorbic Acid Metabolic Process Transepithelial Transport Purine Nucleobase Biosynthetic Process Organic Anion Transport Vitamin Transmembrane Transport Response To Drug Intestinal Absorption Negative Regulation Of Lipid Transport Nucleobase-containing Compound Metabolic Process Cholesterol Efflux Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Anion Transport Glutamine Metabolic Process Regulation Of Cholesterol Transport Small Molecule Metabolic Process Cellular Nitrogen Compound Metabolic Process Purine Nucleobase Metabolic Process Vitamin Transport Excretion Nitrogen Compound Metabolic Process Carbohydrate Transmembrane Transport Pigment Biosynthetic Process Sterol Transport Cholesterol Transport Purine Ribonucleoside Monophosphate Biosynthetic Process Cholesterol Homeostasis Sterol Homeostasis Carboxylic Acid Metabolic Process Water-soluble Vitamin Metabolic Process
Tagcloud ?			abhd5 anomaly atgl cgi ctgm dgat1 diverge enteropathy gk glycerol gpd1 hsl ichthyosis inborn jordan lipe lipodystrophy loosing lpin1 lpin2 majeed nlsd perilipin pnpla2 pseudohypertriglyceridemia rhabdomyolysis steatosis tgs vacuolated
Tagcloud (Difference) ?			abhd5 anomaly atgl cgi ctgm dgat1 diverge enteropathy gk glycerol gpd1 hsl ichthyosis inborn jordan lipe lipodystrophy loosing lpin1 lpin2 majeed nlsd perilipin pnpla2 pseudohypertriglyceridemia rhabdomyolysis steatosis tgs vacuolated
Tagcloud (Intersection) ?