ZNF687 and TSPYL2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (affinity chromatography technology, two hybrid, affinity chromatography technology)

		ZNF687	TSPYL2
Description		zinc finger protein 687	TSPY like 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Chromatin Nucleus Nucleoplasm Nucleolus Cytoplasm
	Molecular Function	DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Metal Ion Binding	RDNA Binding Chromatin Binding Protein Binding Histone Binding
	Biological Process	Regulation Of DNA-templated Transcription	Chromatin Organization Nucleosome Assembly Negative Regulation Of DNA Replication Regulation Of Signal Transduction Negative Regulation Of Cell Growth Negative Regulation Of Cell Cycle Regulation Of Protein Kinase Activity
Pathways			XBP1(S) activates chaperone genes
Drugs
Diseases
GWAS		Body mass index ( 26426971)
Interacting Genes		2 interacting genes: CDKN2A TSPYL2	51 interacting genes: ABT1 AEBP2 APTX CASK CCNB1 CDK1 CDK2 CDK4 CEP19 COIL CREBBP CSNK2A1 DYRK1A EEF1A1 EZH2 GFI1B H2BC15 H3C1 HMGXB4 INO80B KDM6A KDM6B KMT5B LMO2 LNX1 MCRS1 NOL12 NOP53 PHF19 RBM15 RNF151 RPS25 SIRT6 SNIP1 TBC1D26 TMA16 TNNT1 TSPYL1 XAGE1A XAGE1B YAP1 ZBTB24 ZBTB48 ZFP1 ZNF280C ZNF286A ZNF329 ZNF524 ZNF687 ZNF775 ZNF835
Entrez ID		57592	64061
HPRD ID		13859	06713
Ensembl ID		ENSG00000143373	ENSG00000184205
Uniprot IDs		Q8N1G0	Q9H2G4
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Protein Kinase Activity Regulation Of Kinase Activity Negative Regulation Of Cell-matrix Adhesion Regulation Of Protein Phosphorylation Regulation Of Phosphorylation Negative Regulation Of Cell-substrate Adhesion Protein Destabilization Cellular Response To Hydrogen Peroxide Regulation Of Mitochondrial Membrane Potential Regulation Of Phosphorus Metabolic Process Regulation Of Catalytic Activity Regulation Of Protein Modification Process Response To Hydrogen Peroxide Positive Regulation Of Protein Localization To Nucleus Ligase Inhibitor Activity Cellular Response To Reactive Oxygen Species Mitochondrial Threonyl-tRNA Aminoacylation Regulation Of Protein Serine/threonine Kinase Activity Regulation Of Cell-matrix Adhesion Negative Regulation Of DNA Metabolic Process Regulation Of Protein Localization To Nucleus Response To Reactive Oxygen Species Negative Regulation Of Cell Growth Positive Regulation Of Macrophage Apoptotic Process Apoptotic Process Involved In Mammary Gland Involution Positive Regulation Of Platelet-derived Growth Factor Receptor-beta Signaling Pathway Threonine-tRNA Ligase Activity Threonyl-tRNA Aminoacylation Negative Regulation Of Leukocyte Activation Positive Regulation Of Apoptotic Process Involved In Mammary Gland Involution Negative Regulation Of Growth Cellular Response To Oxidative Stress Regulation Of Cell-substrate Adhesion Senescence-associated Heterochromatin Focus Negative Regulation Of Cell Activation Cellular Response To Progesterone Stimulus Negative Regulation Of Protein Neddylation Ubiquitin-protein Transferase Inhibitor Activity Negative Regulation Of Mammary Gland Epithelial Cell Proliferation Negative Regulation Of Immature T Cell Proliferation In Thymus Connexin Binding Mitochondrial Depolarization Oncogene-induced Cell Senescence Cellular Response To Chemical Stress Negative Regulation Of Immature T Cell Proliferation Positive Regulation Of Apoptotic Process Involved In Morphogenesis Regulation Of Intracellular Transport Negative Regulation Of Neutrophil Activation Regulation Of Caveolin-mediated Endocytosis Positive Regulation Of Dephosphorylation	Nucleus Chromatin Organization Regulation Of Transcription By RNA Polymerase II Chromatin Remodeling Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Nucleoplasm Regulation Of Macromolecule Metabolic Process Nucleolus Regulation Of Primary Metabolic Process Regulation Of Metabolic Process DNA Repair RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA Binding DNA Metabolic Process Chromatin Binding Zinc Ion Binding DNA Damage Response G1/S Transition Of Mitotic Cell Cycle Cell Cycle G1/S Phase Transition Chromatin DNA Binding Transcription Regulator Complex Cyclin B1-CDK1 Complex Positive Regulation Of Nucleobase-containing Compound Metabolic Process ESC/E(Z) Complex Positive Regulation Of Chromosome Organization Regulation Of G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of DNA Metabolic Process Cyclin-dependent Protein Kinase Activity Regulation Of Cell Cycle G2/M Phase Transition Metal Ion Binding Cellular Response To Stress Telomere Organization Positive Regulation Of RNA Metabolic Process Regulation Of Cell Cycle Phase Transition Positive Regulation Of Mitochondrial ATP Synthesis Coupled Electron Transport Histone H3K27me2/H3K27me3 Demethylase Activity Negative Regulation Of Cell Cycle Phase Transition Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of DNA Repair Protein Localization To Site Of Double-strand Break Regulation Of DNA Repair Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of Cardiac Muscle Cell Proliferation Cyclin-dependent Protein Serine/threonine Kinase Activity
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