AICDA and RNF126

Number of citations of the paper that reports this interaction (PMID 23277564)
6

Data Source:
BioGRID (biochemical, affinity chromatography technology, enzymatic study)

		AICDA	RNF126
Gene Name		activation-induced cytidine deaminase	ring finger protein 126
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Exosome (RNase Complex) Nucleus Cytoplasm	Nucleus Cytoplasm
	Molecular Function	Cytidine Deaminase Activity Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Binding	Epidermal Growth Factor Receptor Binding Protein Binding Zinc Ion Binding Ligase Activity Ubiquitin Protein Ligase Activity
	Biological Process	MRNA Processing Cytidine Deamination Somatic Diversification Of Immunoglobulins Somatic Hypermutation Of Immunoglobulin Genes B Cell Differentiation Isotype Switching Cellular Response To Lipopolysaccharide DNA Demethylation Negative Regulation Of Methylation-dependent Chromatin Silencing	Protein Monoubiquitination Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Cell Proliferation Retrograde Transport, Endosome To Golgi Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Protein K63-linked Ubiquitination Protein K48-linked Ubiquitination Cytoplasm-associated Proteasomal Ubiquitin-dependent Protein Catabolic Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: APP NEDD4L PRKDC PSME3 RNF126 RPA1	26 interactors: AICDA BAG6 CDKN1A CSNK2B EGFR HMGCL MDM2 NUDT3 OTUB1 OTUB2 PLK1 PSMF1 RBX1 SNUPN TRIM11 TRIM23 TRIM26 TRIM52 TSG101 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2N USP15 USP2
Entrez ID		57379	55658
HPRD ID		05585	11501
Ensembl ID		ENSG00000111732	ENSG00000070423
Uniprot IDs		Q546Y9 Q7Z599 Q9GZX7	A8K0Q1 Q9BV68
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Polyubiquitination Response To Stress Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle Phase Transition Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Cellular Macromolecule Catabolic Process Proteasomal Protein Catabolic Process Protein K48-linked Ubiquitination Protein Monoubiquitination Response To Abiotic Stimulus Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Signal Transduction Involved In DNA Damage Checkpoint Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Signal Transduction Involved In Cell Cycle Checkpoint Regulation Of Mitotic Cell Cycle Mitotic G1 DNA Damage Checkpoint Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Homeostatic Process Telomere Maintenance Double-strand Break Repair Via Homologous Recombination Regulation Of Cell Cycle Process Recombinational Repair Regulation Of ERBB Signaling Pathway Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Signal Transduction In Response To DNA Damage Cellular Response To Stress Proteolysis Involved In Cellular Protein Catabolic Process Mitotic DNA Damage Checkpoint Cellular Protein Modification Process Cellular Protein Catabolic Process Cytoplasm-associated Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Mitotic DNA Integrity Checkpoint Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein Catabolic Process Catabolic Process Mitotic Cell Cycle Process Regulation Of G1/S Transition Of Mitotic Cell Cycle Cellular Homeostasis Regulation Of Cell Cycle G1/S Phase Transition Cellular Response To Stimulus Synaptic Growth At Neuromuscular Junction Positive Regulation Of Caveolin-mediated Endocytosis Negative Regulation Of Mitotic Cell Cycle Phase Transition Double-strand Break Repair	Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Cellular Protein Modification Process Protein Catabolic Process Protein Ubiquitination Protein Modification By Small Protein Conjugation Cellular Macromolecule Catabolic Process Catabolic Process Proteolysis Cellular Protein Metabolic Process Regulation Of Proteasomal Protein Catabolic Process Regulation Of Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Protein Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Protein Polyubiquitination Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Protein K48-linked Ubiquitination Immune System Process Innate Immune Response Negative Regulation Of Mitotic Cell Cycle Cellular Response To Oxygen Levels Regulation Of Nitrogen Compound Metabolic Process Cellular Response To DNA Damage Stimulus Cellular Metabolic Process Negative Regulation Of Protein Catabolic Process Regulation Of Mitotic Cell Cycle Cellular Response To Stress Regulation Of Cellular Protein Metabolic Process Regulation Of Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Negative Regulation Of Cell Cycle Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Negative Regulation Of Mitotic Cell Cycle Phase Transition Immune Response-regulating Signaling Pathway Immune Response Positive Regulation Of Cell Cycle Cell Cycle Negative Regulation Of Proteasomal Protein Catabolic Process Mitotic Cell Cycle Checkpoint Regulation Of Gene Expression Regulation Of Protein Metabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Cellular Protein Catabolic Process Positive Regulation Of Ligase Activity
Tagcloud ?		125b 181b 19a 20a 23b 30a autoantibody bach2 bcl6 blimp csr cytidine dampened deaminase hoxc4 hypermutated hypermutation irf4 lpr mrl pax5 prdm1 rev1 shm silence switched underpin ung valproic	cargo cathepsin cation cholera depleted dispersed e3 endosomal endosomes finger furin internalization lastly ligase lysosomal mannose missorting mpr proteasome rab4 rescue retrograde route sorting tgn38 toxin transiently ubiquitin unaffected
Tagcloud (Difference) ?		125b 181b 19a 20a 23b 30a autoantibody bach2 bcl6 blimp csr cytidine dampened deaminase hoxc4 hypermutated hypermutation irf4 lpr mrl pax5 prdm1 rev1 shm silence switched underpin ung valproic	cargo cathepsin cation cholera depleted dispersed e3 endosomal endosomes finger furin internalization lastly ligase lysosomal mannose missorting mpr proteasome rab4 rescue retrograde route sorting tgn38 toxin transiently ubiquitin unaffected
Tagcloud (Intersection) ?