INTS12 and FAM9A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		INTS12	FAM9A
Description		integrator complex subunit 12	family with sequence similarity 9 member A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Integrator Complex INTAC Complex	Synaptonemal Complex Nucleus Nucleolus
	Molecular Function	Protein Binding Zinc Ion Binding Metal Ion Binding	Protein Binding
	Biological Process	SnRNA Processing Regulation Of Transcription Elongation By RNA Polymerase II SnRNA 3'-end Processing RNA Polymerase II Transcription Initiation Surveillance	Spermatid Development Meiotic Cell Cycle
Pathways		RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes
Drugs
Diseases
GWAS		Asthma ( 31959851) Chronic obstructive pulmonary disease ( 30804561) Lung function (FEV1) ( 24023788) Night sleep phenotypes ( 27126917) Post bronchodilator FEV1 ( 26634245) Pulmonary function ( 20010835) Pulmonary function (smoking interaction) ( 23284291) Weight ( 28548082)	Age at voice drop ( 27182965) Creatinine levels ( 29403010) Estradiol levels ( 34255042) Glomerular filtration rate ( 29403010) Hematocrit ( 29403010) Hemoglobin ( 29403010) Male-pattern baldness ( 27182965)
Interacting Genes		4 interacting genes: APP CEBPA FAM9A HAPSTR1	38 interacting genes: ARPC3 CTNNA3 ESRRA ESRRG FAM9B H2BC15 HOMER1 INTS12 KDM1A KMT5A LCE1E MCRS1 NAB2 NXF1 PHC1 PICK1 PRMT1 PRR20A PRR20B PRR20C PRR20D PRR20E RNF151 RNF4 RUNX1T1 SDCBP STAC3 THAP1 TRAF2 TRAF5 TRIM41 TRIM54 TXLNA VCX ZBTB6 ZDHHC17 ZFP91 ZNF775
Entrez ID		57117	171482
HPRD ID		11271	06506
Ensembl ID		ENSG00000138785	ENSG00000183304
Uniprot IDs		Q96CB8	Q8IZU1
PDB IDs
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Positive Regulation Of Inflammatory Response Regulation Of Response To Calcium Ion Amylin Binding Endosome To Plasma Membrane Transport Vesicle Cell Maturation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cell Development Lipoprotein Particle Memory Notch Signaling Pathway Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Cellular Response To Metal Ion CHOP-C/EBP Complex RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Response To Vitamin B2 C/EBP Complex Positive Regulation Of Proteolysis Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Developmental Maturation Positive Regulation Of Protein Catabolic Process Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling White Fat Cell Proliferation Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Growth Factor Receptor Binding Main Axon Negative Regulation Of Hematopoietic Stem Cell Proliferation Rb-E2F Complex Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Learning Or Memory Axon Choice Point Recognition Response To Phenylpropanoid	Identical Protein Binding Zinc Ion Binding Nucleoplasm Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Histone H4 Methyltransferase Activity Regulation Of RNA Metabolic Process Ubiquitin Protein Ligase Activity Negative Regulation Of RNA Metabolic Process Thioesterase Binding CD40 Signaling Pathway Interleukin-17-mediated Signaling Pathway Estrogen Response Element Binding CD40 Receptor Complex Regulation Of Nucleobase-containing Compound Metabolic Process Protein K63-linked Ubiquitination Signaling Adaptor Activity Regulation Of Double-strand Break Repair Via Homologous Recombination Metal Ion Binding
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