DNAAF19 and CENPN

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		DNAAF19	CENPN
Description		dynein axonemal assembly factor 19	centromere protein N
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Cilium Axoneme Motile Cilium Outer Dynein Arm Cell Projection	Chromosome, Centromeric Region Kinetochore Inner Kinetochore Nucleus Nucleoplasm Chromosome Cytosol
	Molecular Function	Protein Binding Protein Homodimerization Activity	Protein Binding
	Biological Process	Heart Looping Cilium Movement Epithelial Cilium Movement Involved In Extracellular Fluid Movement Determination Of Left/right Symmetry Cell Projection Organization Outer Dynein Arm Assembly Inner Dynein Arm Assembly Epithelial Cilium Movement Involved In Determination Of Left/right Asymmetry Axonemal Dynein Complex Assembly Determination Of Digestive Tract Left/right Asymmetry	Chromosome Segregation CENP-A Containing Chromatin Assembly
Pathways			Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS			Mosaic loss of chromosome Y (Y chromosome dosage) ( 28346444 31624269) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		17 interacting genes: CENPN GRIPAP1 HGS MEOX1 MEOX2 PAX6 PICK1 PKN1 PLAAT1 PNMA6A PRKAR1B R3HCC1L RCN3 RUVBL2 SUOX USHBP1 VAC14	4 interacting genes: ALKBH7 DNAAF19 OSGIN1 TSSK3
Entrez ID		388389	55839
HPRD ID		14200	12528
Ensembl ID		ENSG00000167131	ENSG00000166451
Uniprot IDs		Q8IW40	Q96H22
PDB IDs			6BUZ 6C0W 6EQT 6MUO 6MUP 7PKN 7QOO 7R5S 7R5V 7U46 7U47 7U4D 7XHN 7XHO 7YWX 7YYH
Enriched GO Terms of Interacting Partners?		Somite Specification Segment Specification HMG Box Domain Binding Somite Development Regulation Of Vesicle-mediated Transport RNA Polymerase II Core Promoter Sequence-specific DNA Binding
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