DNAAF19 and PLAAT1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		DNAAF19	PLAAT1
Description		dynein axonemal assembly factor 19	phospholipase A and acyltransferase 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Cilium Axoneme Motile Cilium Outer Dynein Arm Cell Projection	Nucleus Nuclear Envelope Lumen Cytoplasm Mitochondrion Lysosome Endoplasmic Reticulum Cytosol Membrane
	Molecular Function	Protein Binding Protein Homodimerization Activity	Phospholipase Activity Phospholipase A2 Activity Protein Binding O-acyltransferase Activity Phospholipase A1 Activity N-acyltransferase Activity Transferase Activity Hydrolase Activity
	Biological Process	Heart Looping Cilium Movement Epithelial Cilium Movement Involved In Extracellular Fluid Movement Determination Of Left/right Symmetry Cell Projection Organization Outer Dynein Arm Assembly Inner Dynein Arm Assembly Epithelial Cilium Movement Involved In Determination Of Left/right Asymmetry Axonemal Dynein Complex Assembly Determination Of Digestive Tract Left/right Asymmetry	Lipid Metabolic Process Lipid Catabolic Process Phosphatidylcholine Metabolic Process N-acylphosphatidylethanolamine Metabolic Process Lens Fiber Cell Differentiation Organelle Disassembly
Pathways			Acyl chain remodelling of PE
Drugs
Diseases
GWAS
Interacting Genes		17 interacting genes: CENPN GRIPAP1 HGS MEOX1 MEOX2 PAX6 PICK1 PKN1 PLAAT1 PNMA6A PRKAR1B R3HCC1L RCN3 RUVBL2 SUOX USHBP1 VAC14	7 interacting genes: APP DNAAF19 GPANK1 HGS TLX3 UBQLN1 ZIC1
Entrez ID		388389	57110
HPRD ID		14200	07577
Ensembl ID		ENSG00000167131	ENSG00000127252
Uniprot IDs		Q8IW40	Q9HDD0
PDB IDs
Enriched GO Terms of Interacting Partners?		Somite Specification Segment Specification HMG Box Domain Binding Somite Development Regulation Of Vesicle-mediated Transport RNA Polymerase II Core Promoter Sequence-specific DNA Binding	Central Nervous System Development Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Adult Locomotory Behavior Regulation Of Calcium Ion Transmembrane Transport Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Regulation Of Response To Calcium Ion Axon Midline Choice Point Recognition Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Amyloid Fibril Formation Adult Behavior Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Regulation Of Response To Endoplasmic Reticulum Stress Positive Regulation Of Response To Endoplasmic Reticulum Stress Regulation Of Protein Catabolic Process Lipoprotein Particle Regulation Of Protein Localization To Nucleus Growth Factor Receptor Binding Main Axon Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Regulation Of Transport Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling ESCRT-0 Complex Phagocytic Vesicle Lumen Macroautophagy Negative Regulation Of Store-operated Calcium Channel Activity Negative Regulation Of Toll-like Receptor 3 Signaling Pathway Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Neuron Differentiation Regulation Of Toll Signaling Pathway Locomotory Behavior Positive Regulation Of Proteolysis Axon Choice Point Recognition
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