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MKI67
Description
marker of proliferation Ki-67
Image
GO Annotations
Cellular Component
Condensed Chromosome
Nucleus
Nucleoplasm
Chromosome
Nucleolus
Membrane
Molecular Function
Nucleotide Binding
DNA Binding
RNA Binding
Protein Binding
ATP Binding
Molecular Condensate Scaffold Activity
Biological Process
Chromosome Segregation
Regulation Of Mitotic Nuclear Division
Cell Population Proliferation
Regulation Of Chromatin Organization
Pathways
Drugs
Diseases
GWAS
Alzheimer's disease in APOE e4- carriers (
25778476
)
Drug experimentation measurement (
30718321
)
Lead levels (
26025379
)
Select biomarker traits (
17903293
)
Suicide attempt severity in mood disorders (
33783297
)
Triglyceride levels x loop diuretics use interaction (
31806883
)
Novel Interacting Genes
1 novel interacting genes:
DRD4
Interacting Genes
18 interacting genes:
CBX3
CBX5
CDC20
CDH1
CDK1
CEBPA
ECPAS
HINFP
KIF15
NIFK
PPP1CA
PRKCB
PTEN
SMN1
SUMO2
TK1
TRIM55
TRIM63
Entrez ID
4288
HPRD ID
08902
Ensembl ID
ENSG00000148773
Uniprot IDs
P46013
PDB IDs
1R21
2AFF
5J28
Enriched GO Terms of Interacting Partners
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DNA Synthesis Involved In Mitotic DNA Replication
Chromatin Binding
Rhythmic Process
Thymidine Biosynthetic Process
Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Proteolysis Involved In Protein Catabolic Process
Thymidine Metabolic Process
Nucleobase-containing Compound Biosynthetic Process
Nucleoplasm
Negative Regulation Of Cell Cycle
Chromosome, Telomeric Region
Regulation Of Ubiquitin-dependent Protein Catabolic Process
Anaphase-promoting Complex Binding
Identical Protein Binding
Macromolecule Metabolic Process
Mitotic Nuclear Membrane Disassembly
Positive Regulation Of Proteolysis
Ubiquitin Ligase Activator Activity
Pyrimidine Nucleoside Metabolic Process
Negative Regulation Of Cell Cycle Phase Transition
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Postsynapse
Spindle
Nuclear Membrane Disassembly
Cellular Response To Lithium Ion
Response To Stress
Membrane Disassembly
Spindle Assembly
Response To Lithium Ion
Protein Modification Process
Negative Regulation Of Cell Cycle Process
PML Body
Nucleus
Regulation Of Circadian Rhythm
Positive Regulation Of Proteasomal Protein Catabolic Process
Regulation Of Primary Metabolic Process
Microtubule Cytoskeleton Organization Involved In Mitosis
Histone Deacetylase Binding
Regulation Of Generation Of Precursor Metabolites And Energy
Response To Glucocorticoid
Response To Metal Ion
Presynaptic Cytosol
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Cellular Component Assembly
Pericentric Heterochromatin
Mitotic Cell Cycle Phase Transition
Centrosome
Macromolecule Biosynthetic Process
Response To Corticosteroid
Regulation Of Nucleobase-containing Compound Metabolic Process
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