RGMA and SGSM2

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		RGMA	SGSM2
Gene Name		repulsive guidance molecule family member a	small G protein signaling modulator 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Plasma Membrane Anchored Component Of Membrane Extracellular Vesicular Exosome
	Molecular Function	Coreceptor Activity	Rab GTPase Activator Activity Rab GTPase Binding
	Biological Process	Axon Guidance BMP Signaling Pathway	Positive Regulation Of Rab GTPase Activity Late Endosome To Golgi Transport
Pathways		Axon guidance Netrin-1 signaling
Drugs
Diseases
GWAS		Response to angiotensin II receptor blocker therapy (opposite direction w/ diuretic therapy) ( 22566498) Type 1 diabetes nephropathy ( 23028342)	Aortic root size ( 19584346) Proinsulin levels ( 21873549)
Protein-Protein Interactions		3 interactors: PPP1R16A SGSM2 TERF2IP	14 interactors: AFP CA12 CELSR3 CHD3 EGFR FNBP1L GDPD2 ILF2 KHDRBS3 MPP1 PNO1 PTN RGMA RPS25
Entrez ID		56963	9905
HPRD ID		09560	15284
Ensembl ID		ENSG00000182175	ENSG00000141258
Uniprot IDs		B7Z5S8 Q96B86	B9A6J3 O43147
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of DNA Recombination At Telomere Late Endosome To Golgi Transport Protection From Non-homologous End Joining At Telomere Protein Localization To Chromosome, Telomeric Region Telomere Capping Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Double-strand Break Repair Via Homologous Recombination Regulation Of Telomere Maintenance RNA-dependent DNA Replication Negative Regulation Of DNA Recombination Regulation Of Double-strand Break Repair Protein Localization To Chromosome Telomere Maintenance Via Telomere Lengthening Regulation Of DNA Repair Retrograde Transport, Endosome To Golgi Regulation Of Intracellular Signal Transduction Regulation Of DNA Recombination Telomere Maintenance Negative Regulation Of Chromosome Organization Negative Regulation Of DNA Metabolic Process Positive Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of Rab GTPase Activity Cellular Localization Regulation Of Rab GTPase Activity Regulation Of Rab Protein Signal Transduction Regulation Of Response To DNA Damage Stimulus
Tagcloud ?		anova clinicopathological comparisons connection correct demethylation dfa discriminant expressions ezh2 factorial gleason h3k27me3 mark marks methyltransferase obviously pca pgr prostate psa qpcr quantify repressive src3 stratification tissues tukey variance
Tagcloud (Difference) ?		anova clinicopathological comparisons connection correct demethylation dfa discriminant expressions ezh2 factorial gleason h3k27me3 mark marks methyltransferase obviously pca pgr prostate psa qpcr quantify repressive src3 stratification tissues tukey variance
Tagcloud (Intersection) ?