SEMA3G and DESI2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SEMA3G	DESI2
Description		semaphorin 3G	desumoylating isopeptidase 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Extracellular Exosome	Cytoplasm
	Molecular Function	Signaling Receptor Binding Protein Binding Semaphorin Receptor Binding Neuropilin Binding Chemorepellent Activity	Cysteine-type Deubiquitinase Activity Protein Binding Peptidase Activity Palmitoyl-(protein) Hydrolase Activity Hydrolase Activity Long-chain Fatty Acyl-CoA Hydrolase Activity K63-linked Deubiquitinase Activity Deubiquitinase Activity K48-linked Deubiquitinase Activity
	Biological Process	Neural Crest Cell Migration Axon Guidance Positive Regulation Of Cell Migration Negative Regulation Of Axon Extension Forebrain Development Negative Chemotaxis Semaphorin-plexin Signaling Pathway	Proteolysis Macromolecule Depalmitoylation
Pathways
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 21926972) Blood protein levels ( 30072576) Schizophrenia ( 23974872) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		2 interacting genes: DESI2 RHOU	11 interacting genes: ARFIP1 BNIP2 COQ8A MYG1 NFU1 PBX3 PLIN2 SEMA3G SH3GLB1 SPART THAP7
Entrez ID		56920	51029
HPRD ID		14251	15153
Ensembl ID		ENSG00000010319	ENSG00000121644
Uniprot IDs		Q9NS98	Q9BSY9
PDB IDs
Enriched GO Terms of Interacting Partners?		Macromolecule Depalmitoylation Palmitoyl-(protein) Hydrolase Activity Long-chain Fatty Acyl-CoA Hydrolase Activity K63-linked Deubiquitinase Activity K48-linked Deubiquitinase Activity Positive Regulation Of Focal Adhesion Disassembly Macromolecule Deacylation Deubiquitinase Activity Rac Protein Signal Transduction Positive Regulation Of Establishment Of Protein Localization To Mitochondrion Positive Regulation Of Protein Targeting To Mitochondrion Podosome Regulation Of Protein Targeting To Mitochondrion Cysteine-type Deubiquitinase Activity Regulation Of Cell-substrate Junction Organization Cell Cycle G1/S Phase Transition G1/S Transition Of Mitotic Cell Cycle Establishment Of Cell Polarity	Lipid Droplet Lipid Droplet Organization Cellular Response To Glucose Starvation Posterior Compartment Specification Anterior Compartment Pattern Formation Midbody Negative Regulation Of Collateral Sprouting In Absence Of Injury Negative Regulation Of Axonogenesis Negative Regulation Of Retrograde Transport, Endosome To Golgi Protein Localization To Vacuolar Membrane
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