MAP3K7CL and FAM3B

		MAP3K7CL	FAM3B
Description		MAP3K7 C-terminal like	FAM3 metabolism regulating signaling molecule B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol	Extracellular Region Extracellular Space Extracellular Exosome
	Molecular Function	Protein Binding	Cytokine Activity Protein Binding Carbohydrate Binding
	Biological Process		Apoptotic Process Signal Transduction Insulin Secretion
Pathways
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 33547301) Coronary artery disease ( 29212778 33020668) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Estimated glomerular filtration rate after 1 year in renal transplantation (recipient effect) ( 30920136) Gamma glutamyl transferase levels ( 29403010 33339817) Ventricular ectopy ( 29618737) White blood cell count ( 32888494)	Blood protein levels ( 30072576) Elevated serum carcinoembryonic antigen levels ( 24941225) Glycemic traits (pregnancy) ( 23903356) L1-L4 bone mineral density x serum urate levels interaction ( 34046847) Tumor biomarkers ( 23300138)
Interacting Genes		10 interacting genes: AK8 CISH CRYAA DDIT4L GPS2 KRT31 KRT34 REL TAB3 USF1	1 interacting genes: APP
Entrez ID		56911	54097
HPRD ID		10764	10552
Ensembl ID		ENSG00000156265	ENSG00000183844
Uniprot IDs		B0EVZ6 B0EVZ7 B0EVZ8 B4DFW0 P57077	P58499
PDB IDs
Enriched GO Terms of Interacting Partners?		Structural Molecule Activity Non-canonical NF-kappaB Signal Transduction	Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Regulation Of Response To Calcium Ion Positive Regulation Of Tumor Necrosis Factor Production Amylin Binding Endosome To Plasma Membrane Transport Vesicle Antibacterial Humoral Response Protein Tetramerization Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Defense Response To Gram-positive Bacterium Defense Response Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Locomotion Positive Regulation Of Tumor Necrosis Factor Superfamily Cytokine Production Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Collagen Type VI Trimer Multicellular Organismal Locomotion Response To Polyamine Macromolecule Pinceau Fiber Methylglyoxal Reductase (NADPH) (acetol Producing) Activity Regulation Of Spontaneous Synaptic Transmission Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Regulation Of Tumor Necrosis Factor Production NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Endocytosis Cellular Response To Norepinephrine Stimulus Regulation Of Toll Signaling Pathway Growth Factor Receptor Binding Main Axon Antimicrobial Humoral Response Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Response To Bleomycin Apoptotic Nuclear Changes Skeletal Muscle Tissue Growth
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