FAM3B

Name	FAM3 metabolism regulating signaling molecule B
Structure	No pdb structure
Novel Interactors	6 novel interactors: BIN2 COL6A1 FCGR2A H2BC12L KCNAB2 MAP3K7CL
Interactors	1 interactors: APP
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Extracellular Exosome
	Molecular Function	Cytokine Activity Protein Binding Carbohydrate Binding
	Biological Process	Apoptotic Process Signal Transduction Insulin Secretion
GWAS	Blood protein levels ( 30072576 ) Elevated serum carcinoembryonic antigen levels ( 24941225 ) Glycemic traits (pregnancy) ( 23903356 ) L1-L4 bone mineral density x serum urate levels interaction ( 34046847 ) Tumor biomarkers ( 23300138 )
Entrez ID	54097
HPRD ID	10552
Ensembl ID	ENSG00000183844
Uniprot IDs	P58499
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Regulation Of Response To Calcium Ion Positive Regulation Of Tumor Necrosis Factor Production Amylin Binding Endosome To Plasma Membrane Transport Vesicle Antibacterial Humoral Response Protein Tetramerization Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Defense Response To Gram-positive Bacterium Defense Response Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Locomotion Positive Regulation Of Tumor Necrosis Factor Superfamily Cytokine Production Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Collagen Type VI Trimer Multicellular Organismal Locomotion Response To Polyamine Macromolecule Pinceau Fiber Methylglyoxal Reductase (NADPH) (acetol Producing) Activity Regulation Of Spontaneous Synaptic Transmission Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Regulation Of Tumor Necrosis Factor Production NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Endocytosis Cellular Response To Norepinephrine Stimulus Regulation Of Toll Signaling Pathway Growth Factor Receptor Binding Main Axon Antimicrobial Humoral Response Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Response To Bleomycin Apoptotic Nuclear Changes Skeletal Muscle Tissue Growth