RETN and SF3A2

Number of citations of the paper that reports this interaction (PubMedID 8211113)
0

Data Source:
HPRD (in vitro)

		RETN	SF3A2
Description		resistin	splicing factor 3a subunit 2
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Azurophil Granule Lumen Specific Granule Lumen Extracellular Exosome	Nucleus Nucleoplasm Spliceosomal Complex U2-type Spliceosomal Complex U2 SnRNP Nuclear Speck U2-type Prespliceosome U2-type Precatalytic Spliceosome Catalytic Step 2 Spliceosome
	Molecular Function	Hormone Activity Protein Binding	Nucleic Acid Binding RNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Signal Transduction Response To Mechanical Stimulus Response To Insulin Fat Cell Differentiation Positive Regulation Of Synaptic Transmission Negative Regulation Of Feeding Behavior Positive Regulation Of Progesterone Secretion	Spliceosomal Complex Assembly MRNA 3'-splice Site Recognition MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Positive Regulation Of Neuron Projection Development U2-type Prespliceosome Assembly
Pathways		Neutrophil degranulation FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes	mRNA Splicing - Major Pathway
Drugs			Copper
Diseases
GWAS		Blood protein levels ( 30072576) Menarche (age at onset) ( 25231870) Resistin levels ( 22843503 24123702 27664181 32876488)	Adult body size ( 32376654) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Myocardial infarction ( 24916648) Pulse pressure ( 26390057)
Interacting Genes		3 interacting genes: A2M GPR25 SF3A2	23 interacting genes: APBB1 ASPH BAIAP2 BEND2 CDC42 CEBPA GRB2 HTATSF1 LIN54 NCK2 OGT OSTF1 PRPF40A RCAN1 RETN SF3A1 SH3RF1 SMURF2 TCERG1 TFG TRIP10 VEZF1 YY1
Entrez ID		56729	8175
HPRD ID		05714	02877
Ensembl ID		ENSG00000104918	ENSG00000104897
Uniprot IDs		Q9HD89	Q05DF2 Q15428
PDB IDs			5Z56 5Z57 5Z58 6AH0 6AHD 6FF4 6FF7 6QX9 6Y53 6Y5Q 7ABG 7ABH 7ABI 7EVO 7ONB 7Q4O 7Q4P 7QTT 7VPX 8CH6 8H6E 8H6J 8H6K 8H6L 8HK1 8I0P 8I0R 8I0S 8I0T 8QO9 8QXD 8QZS 8R08 8R09 8R0A 8R0B 8RM5
Enriched GO Terms of Interacting Partners?		Interleukin-8 Binding Negative Regulation Of Complement Activation, Lectin Pathway Tumor Necrosis Factor Binding Interleukin-1 Binding MRNA 3'-splice Site Recognition Negative Regulation Of Complement Activation U2-type Prespliceosome Regulation Of Complement Activation U2-type Prespliceosome Assembly U2-type Spliceosomal Complex U2 SnRNP MRNA Splice Site Recognition Growth Factor Binding Regulation Of Humoral Immune Response Endopeptidase Inhibitor Activity Spliceosomal Complex Assembly U2-type Precatalytic Spliceosome	Nuclear Speck Nucleoplasm Proline-rich Region Binding Signal Transduction Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Proteolysis Positive Regulation Of Supramolecular Fiber Organization Regulation Of Protein-containing Complex Assembly Positive Regulation Of Cytoskeleton Organization Identical Protein Binding Response To Hormone Positive Regulation Of Protein Polymerization Positive Regulation Of Actin Filament Polymerization U2-type Prespliceosome MRNA Cis Splicing, Via Spliceosome Regulation Of Actin Filament Organization Cytoskeletal Anchor Activity Positive Regulation Of Organelle Organization U2-type Prespliceosome Assembly Regulation Of Developmental Process Regulation Of Actin Filament Polymerization U2 SnRNP Regulation Of Multicellular Organismal Process Nuclear Matrix U2-type Spliceosomal Complex Intracellular Signaling Cassette Negative Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Transcription By RNA Polymerase II Wnt Signaling Pathway, Planar Cell Polarity Pathway Regulation Of Actin Cytoskeleton Organization Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Cell Development RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Regulation Of Actin Polymerization Or Depolymerization Guanyl-nucleotide Exchange Factor Adaptor Activity Regulation Of Actin Filament Length Vesicle Membrane Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly RNA Splicing Dendritic Spine Cytoplasm Neuron Projection Branch Point Positive Regulation Of Progesterone Secretion Regulation Of Proteolysis Positive Regulation Of Cell Communication Regulation Of Actin Filament-based Process Positive Regulation Of Signaling
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