GKN1 and TMEM179B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GKN1	TMEM179B
Description		gastrokine 1	transmembrane protein 179B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm Golgi Apparatus Endomembrane System Secretory Granule	Nucleolus Plasma Membrane Membrane Nuclear Speck Secretory Granule Membrane Azurophil Granule Membrane Ficolin-1-rich Granule Membrane
	Molecular Function	Protein Binding Growth Factor Activity	Protein Binding
	Biological Process	Signal Transduction Digestion Positive Regulation Of Cell Population Proliferation Regulation Of Cell Population Proliferation Positive Regulation Of Cell Division
Pathways			Neutrophil degranulation
Drugs
Diseases
GWAS			Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		12 interacting genes: AQP6 CDC27 FAM209A MFF PLPP6 SERP1 SERP2 SMCO4 TMEM179B TREX1 UBE2J1 VAPA	47 interacting genes: ADIPOQ BTN2A2 C1QL4 C2CD2L C3orf52 CCDC167 CCL3L3 CCL4 CCL4L2 CD68 CLCA4 CLCN7 CLDN1 CLDN6 CTXN3 CYB561 DERL3 ERGIC3 FAM163A FATE1 FCER1G FXYD3 GALNT15 GKN1 GPR151 GUCA2A IGFBP5 KRTAP12-2 KTN1 LRP10 LYG1 MARCHF2 MFSD6 PLN SERP2 SLC1A1 SLC22A1 SLC52A1 SLC61A1 STX8 TM4SF19 TMEM14A TMEM236 TMEM237 TMEM242 TMEM47 TRARG1
Entrez ID		56287	374395
HPRD ID		16217	14186
Ensembl ID		ENSG00000169605	ENSG00000185475
Uniprot IDs		A0A8I5KHR1 Q53YU7 Q9NS71	G3V185 Q7Z7N9
PDB IDs
Enriched GO Terms of Interacting Partners?		Endoplasmic Reticulum Membrane Nitrate Transmembrane Transporter Activity Membrane Azurophil Granule Membrane Endoplasmic Reticulum Immune Complex Formation Adenyl Deoxyribonucleotide Binding Immune Response In Brain Or Nervous System Response To Endoplasmic Reticulum Stress Nuclear Inner Membrane Isoprenoid Diphosphate Phosphatase Activity Farnesyl Diphosphate Catabolic Process Geranylgeranyl Diphosphate Catabolic Process PH-gated Chloride Channel Activity Nitrate Transmembrane Transport Cellular Response To Type I Interferon DNA Exonuclease Activity Retrotransposition Transposition Endoplasmic Reticulum Unfolded Protein Response Response To Unfolded Protein FFAT Motif Binding DNA Synthesis Involved In UV-damage Excision Repair Geranyl Diphosphate Metabolic Process Positive Regulation Of Neutrophil Activation	Membrane Inorganic Anion Transport
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