GKN1 and SERP2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GKN1	SERP2
Description		gastrokine 1	stress associated endoplasmic reticulum protein family member 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm Golgi Apparatus Endomembrane System Secretory Granule	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Protein Binding Growth Factor Activity	Protein Binding
	Biological Process	Signal Transduction Digestion Positive Regulation Of Cell Population Proliferation Regulation Of Cell Population Proliferation Positive Regulation Of Cell Division	Response To Unfolded Protein Endoplasmic Reticulum Unfolded Protein Response
Pathways
Drugs
Diseases
GWAS			Chronic obstructive pulmonary disease ( 30804561) Dupuytren's disease ( 28886342) Fasting insulin (dietary factor interaction) ( 24204828) Homeostasis model assessment of insulin resistance (dietary factor interaction) ( 24204828)
Interacting Genes		12 interacting genes: AQP6 CDC27 FAM209A MFF PLPP6 SERP1 SERP2 SMCO4 TMEM179B TREX1 UBE2J1 VAPA	54 interacting genes: ALG10 AQP6 BIK BSCL2 CERS4 CISD2 CKB CYB561 CYBRD1 EBP ELOVL4 ERGIC3 EWSR1 FAM210B FCGR2A FFAR2 FNDC9 FRMD3 GET1 GKN1 GPR152 GPR42 HSD17B13 KASH5 LHFPL5 LMNA LYVE1 MTIF3 MUC1 NEMP1 OPRM1 PTGES RETREG3 RNASEK SCN3B SLC10A6 SLC30A4 SLC38A1 SLC38A7 SLC71A2 SPACA1 STOM STX1A TIMMDC1 TM4SF18 TM4SF19 TMED8 TMEM106C TMEM14B TMEM179B TMEM237 TMEM31 TMEM80 TMX2
Entrez ID		56287	387923
HPRD ID		16217	16590
Ensembl ID		ENSG00000169605	ENSG00000151778
Uniprot IDs		A0A8I5KHR1 Q53YU7 Q9NS71	Q8N6R1
PDB IDs
Enriched GO Terms of Interacting Partners?		Endoplasmic Reticulum Membrane Nitrate Transmembrane Transporter Activity Membrane Azurophil Granule Membrane Endoplasmic Reticulum Immune Complex Formation Adenyl Deoxyribonucleotide Binding Immune Response In Brain Or Nervous System Response To Endoplasmic Reticulum Stress Nuclear Inner Membrane Isoprenoid Diphosphate Phosphatase Activity Farnesyl Diphosphate Catabolic Process Geranylgeranyl Diphosphate Catabolic Process PH-gated Chloride Channel Activity Nitrate Transmembrane Transport Cellular Response To Type I Interferon DNA Exonuclease Activity Retrotransposition Transposition Endoplasmic Reticulum Unfolded Protein Response Response To Unfolded Protein FFAT Motif Binding DNA Synthesis Involved In UV-damage Excision Repair Geranyl Diphosphate Metabolic Process Positive Regulation Of Neutrophil Activation	Membrane Protein Binding Ascorbate Homeostasis Transmembrane Monodehydroascorbate Reductase Activity Endoplasmic Reticulum Membrane Endoplasmic Reticulum Glutamine Transport L-glutamine Transmembrane Transporter Activity
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