FAM214A and MID2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		FAM214A	MID2
Gene Name		family with sequence similarity 214, member A	midline 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component		Cytoplasm Microtubule Extracellular Vesicular Exosome
	Molecular Function		Microtubule Binding Zinc Ion Binding Ligase Activity Protein Homodimerization Activity Protein Heterodimerization Activity Phosphoprotein Binding
	Biological Process		Protein Ubiquitination Negative Regulation Of Viral Transcription Protein Localization To Microtubule Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Innate Immune Response Negative Regulation Of Viral Entry Into Host Cell Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Viral Release From Host Cell
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: APC GOLGA2 KRT40 LIG4 MAGEA6 MID2 SSX2IP TRIM27	108 interactors: ADAMTSL4 AEN AQP1 ATRIP BCL6B BRCA1 BRMS1L BYSL C19orf66 CALCOCO2 CBX8 CCDC120 CCDC42 CCHCR1 CEP57L1 CHD2 CTSZ DCX DGCR6 DGCR6L DIEXF DMRT3 DYDC1 FAM107A FAM161A FAM214A FAM90A1 FARS2 FBF1 FBXL18 FRMD6 GFI1B GMCL1 GOLGA2 GORASP2 HOXB9 IGBP1 ISCU JOSD1 KIAA1683 KIF1A KIFC3 LENG1 LGALS14 LGALS8 MAGOHB METTL17 MFAP1 MID1 MID1IP1 MOS MVP NR1D2 NXF1 OTUB2 PPP1R18 PRPF31 PSMA1 PTCD2 RCOR3 RPH3AL RPP25L RUNX1T1 SCNM1 SDCBP SLC25A48 SLC25A6 SNAI1 SNAP47 SPATA24 SPG21 SPRY2 STX11 SYT17 TCEA2 TCEB3 THAP7 TOP3B TRIM27 TRIM29 TRIM32 TRIM42 TRIM54 TRPV6 TSGA10 UBE2D1 UBE2D4 UBE2E2 UBE2E3 UBE2U UBTD1 UNC45A UTP23 WT1-AS ZBTB24 ZC2HC1C ZFYVE21 ZGPAT ZNF165 ZNF24 ZNF250 ZNF417 ZNF440 ZNF564 ZNF587 ZNF785 ZNF792 ZSCAN12
Entrez ID		56204	11043
HPRD ID		10965	02191
Ensembl ID		ENSG00000047346
Uniprot IDs		Q32MH5	Q9UJV3
PDB IDs			2DJA 2DMK
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Viral Release From Host Cell Negative Regulation Of Viral Transcription Regulation Of Viral Release From Host Cell T Cell Differentiation In Thymus Somatic Stem Cell Maintenance Regulation Of Viral Transcription Negative Regulation Of Viral Process DNA Ligation Involved In DNA Recombination Positive Regulation Of Protein Polymerization Negative Regulation Of Interleukin-2 Secretion Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process Regulation Of Locomotion Stem Cell Maintenance T Cell Differentiation Regulation Of Viral Process Positive Regulation Of Protein Complex Assembly Negative Regulation Of Odontogenesis Positive Regulation Of Cytoskeleton Organization Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of Calcium Ion Import Lagging Strand Elongation Pro-B Cell Differentiation Intraciliary Transport Involved In Cilium Morphogenesis Negative Regulation Of Protein Kinase Activity Immune System Process Metaphase/anaphase Transition Of Mitotic Cell Cycle Negative Regulation Of Kinase Activity Lymphocyte Differentiation Canonical Wnt Signaling Pathway Involved In Negative Regulation Of Apoptotic Process Protein Localization To Microtubule Establishment Of Integrated Proviral Latency Stem Cell Development Interferon-gamma Secretion Immunoglobulin V(D)J Recombination Establishment Of Viral Latency T Cell Aggregation T Cell Activation Lymphocyte Aggregation Leukocyte Aggregation T Cell Receptor V(D)J Recombination DNA Ligation Involved In DNA Repair Negative Regulation Of Transferase Activity Cytoskeleton Organization Stem Cell Differentiation Positive Regulation Of Cellular Component Biogenesis Lymphoid Progenitor Cell Differentiation Negative Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Positive Regulation Of Microtubule Polymerization Negative Regulation Of Protein Phosphorylation Leukocyte Cell-cell Adhesion	RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Gene Expression Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Transcription, DNA-templated Nitrogen Compound Metabolic Process RNA Biosynthetic Process Protein Polyubiquitination Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Protein K63-linked Ubiquitination Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Protein K48-linked Ubiquitination Negative Regulation Of Nucleic Acid-templated Transcription Biosynthetic Process Cellular Process Regulation Of Gene Expression Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Protein Ubiquitination Protein Modification By Small Protein Conjugation Negative Regulation Of Cellular Metabolic Process Protein K11-linked Ubiquitination Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Maturation Of SSU-rRNA Cellular Metabolic Process Negative Regulation Of Microtubule Depolymerization Protein K6-linked Ubiquitination Regulation Of Microtubule-based Process Ribosomal Small Subunit Biogenesis Regulation Of Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Microtubule Polymerization Or Depolymerization Synaptic Vesicle Fusion To Presynaptic Membrane Negative Regulation Of Transferase Activity Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Viral Release From Host Cell Negative Regulation Of Protein Tyrosine Kinase Activity Regulation Of Microtubule Cytoskeleton Organization Regulation Of Viral Transcription Regulation Of Histone H3-K4 Methylation Regulation Of Microtubule Polymerization Or Depolymerization
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