LIN37 and CDR2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		LIN37	CDR2
Description		lin-37 DREAM MuvB core complex component	cerebellar degeneration related protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Transcription Repressor Complex Myb Complex	Cytoplasm
	Molecular Function	Protein Binding Protein-containing Complex Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Gene Expression G0 To G1 Transition
Pathways		Transcription of E2F targets under negative control by DREAM complex Transcription of E2F targets under negative control by DREAM complex Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 G0 and Early G1 Polo-like kinase mediated events Cyclin E associated events during G1/S transition G1/S-Specific Transcription Cyclin A:Cdk2-associated events at S phase entry
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Refractive error ( 32231278)	Femur bone mineral density x serum urate levels interaction ( 34046847)
Interacting Genes		17 interacting genes: CCNDBP1 CDR2 CEP70 KIFC3 KRT31 KRT40 LZTS2 MAGEA6 MEOX2 PDE4DIP PNMA1 PSTPIP1 TEX11 TFIP11 TRAF1 TRIM54 ZNF76	76 interacting genes: AMOTL2 ANKRD36BP1 AQP1 ARNT2 BEX2 C1orf216 C4orf46 CATSPERT CCDC120 CCDC13 CCDC146 CCDC187 CCDC87 CCHCR1 CDC20 CEP57L1 CHIC2 COX5B DRC12 DRC4 EIF4E2 ENKD1 FAM110A FAM161A FAM50B FAM90A1 FXR1 FZR1 GEM GMPPA HAUS1 HDAC4 HGS KANSL1 KIF5B KIFC3 LENG1 LIN37 MICALL2 MKKS MNS1 MORF4L2 MRPL28 NDN NTAQ1 OAZ2 PKN1 PRKAA2 PRPF18 PSMA1 RCOR3 RSPH14 RUNX1T1 SCNM1 SH2D4A SMARCD1 SMARCE1 TBC1D22B TCHP TEAD4 TEX28 TMCC2 TRIM23 TRIML2 TSC1 TSGA10IP TTC23 TTR TXLNA TXLNB UBTFL1 ZGPAT ZMAT2 ZNF250 ZNF35 ZNF417
Entrez ID		55957	1039
HPRD ID		16872	06681
Ensembl ID		ENSG00000267796	ENSG00000140743
Uniprot IDs		Q96GY3	Q01850
PDB IDs		7N40 7R1D
Enriched GO Terms of Interacting Partners?		Cytoskeleton	Protein Binding Centrosome Cytoskeleton Ciliary Basal Body Microtubule Cytoskeleton Organization Microtubule-based Process Motile Cilium Cytoplasm Positive Regulation Of Anaphase-promoting Complex-dependent Catabolic Process Microtubule Binding Cilium Regulation Of Anaphase-promoting Complex-dependent Catabolic Process Positive Regulation Of Ubiquitin Protein Ligase Activity Cytoskeleton Organization Cell Projection Cilium Organization Polymeric Cytoskeletal Fiber
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