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LIN37

Description lin-37 DREAM MuvB core complex component
Image
GO Annotations Cellular Component
  • Nucleoplasm
  • Transcription Repressor Complex
  • Myb Complex
Molecular Function
  • Protein Binding
  • Protein-containing Complex Binding
Biological Process
  • Negative Regulation Of Transcription By RNA Polymerase II
  • Gene Expression
  • G0 To G1 Transition
Pathways
  • Transcription of E2F targets under negative control by DREAM complex
  • Transcription of E2F targets under negative control by DREAM complex
  • Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1
  • G0 and Early G1
  • Polo-like kinase mediated events
  • Cyclin E associated events during G1/S transition
  • G1/S-Specific Transcription
  • Cyclin A:Cdk2-associated events at S phase entry
Drugs
Diseases
GWAS
  • Brain morphology (MOSTest) ( 32665545)
  • Refractive error ( 32231278)
Interacting Genes 17 interacting genes: CCNDBP1 CDR2 CEP70 KIFC3 KRT31 KRT40 LZTS2 MAGEA6 MEOX2 PDE4DIP PNMA1 PSTPIP1 TEX11 TFIP11 TRAF1 TRIM54 ZNF76
Entrez ID 55957
HPRD ID 16872
Ensembl ID ENSG00000267796
Uniprot IDs Q96GY3
PDB IDs 7N40 7R1D
Enriched GO Terms of Interacting Partners?
  • Cytoskeleton
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© Madhavi K. Ganapathiraju 2012-2025