LANCL2 and TDRKH

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		LANCL2	TDRKH
Description		LanC like glutathione S-transferase 2	tudor and KH domain containing
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Plasma Membrane Membrane Cortical Actin Cytoskeleton	Cytoplasm Mitochondrion P Granule Pi-body PiP-body
	Molecular Function	Protein Binding ATP Binding GTP Binding Phosphatidylinositol-5-phosphate Binding Phosphatidylinositol-3-phosphate Binding Phosphatidylinositol-4-phosphate Binding	Nucleic Acid Binding RNA Binding Protein Binding
	Biological Process	Carbohydrate Metabolic Process Positive Regulation Of Abscisic Acid-activated Signaling Pathway Peptide Modification Negative Regulation Of DNA-templated Transcription	Male Meiotic Nuclear Division Spermatogenesis Fertilization Cell Differentiation P Granule Organization Regulatory NcRNA-mediated Gene Silencing PiRNA Processing
Pathways			PIWI-interacting RNA (piRNA) biogenesis
Drugs
Diseases
GWAS		Impulsivity ( 30718321) Mercury levels ( 26025379) Metabolite levels ( 23823483) QRS interval (sulfonylurea treatment interaction) ( 27958378) Spatial processing ( 31596458)	Asthma ( 30929738 31619474) Coronary artery disease ( 29212778 32469254) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Hemoglobin ( 32888494) Myocardial infarction ( 33532862)
Interacting Genes		9 interacting genes: AKT1 APP APPBP2 RHOU SIAH1 TDRKH TERF2 TERF2IP UBC	7 interacting genes: FAM25A FAM25C FAM25G LANCL2 SNRNP25 ZBTB34 ZFP90
Entrez ID		55915	11022
HPRD ID		13956	15485
Ensembl ID		ENSG00000132434	ENSG00000182134
Uniprot IDs		B3KTN5 Q9NS86	B4DJ68 Q9Y2W6
PDB IDs		6WQ1	2DIQ 3FDR 5J39 6B57 6PI7
Enriched GO Terms of Interacting Partners?		Negative Regulation Of DNA Recombination At Telomere Shelterin Complex Protection From Non-homologous End Joining At Telomere Nuclear Telomere Cap Complex G-rich Strand Telomeric DNA Binding Protein Localization To Chromosome, Telomeric Region Telomere Capping Telomere Maintenance In Response To DNA Damage Enzyme Binding Post-translational Protein Modification RNA-templated DNA Biosynthetic Process Amyloid Fibril Formation Telomeric DNA Binding Regulation Of Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Cellular Component Organization Positive Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Toll-like Receptor Signaling Pathway Modification-dependent Protein Catabolic Process Regulation Of Cellular Response To Stress Negative Regulation Of Telomere Maintenance Positive Regulation Of Nitric Oxide Metabolic Process Protein Ubiquitination Cellular Response To Nerve Growth Factor Stimulus Response To Nerve Growth Factor Regulation Of Nitric Oxide Biosynthetic Process Protein Modification By Small Protein Conjugation Positive Regulation Of DNA Metabolic Process Proteolysis Involved In Protein Catabolic Process Regulation Of TRNA Methylation Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Biotin--[biotin Carboxyl-carrier Protein] Ligase Activity Telomere Cap Complex Negative Regulation Of Telomere Maintenance Via Recombination Negative Regulation Of DNA Recombination Axonal Transport Of Messenger Ribonucleoprotein Complex Negative Regulation Of Telomere Single Strand Break Repair Male Germ Cell Nucleus Regulation Of Nitric Oxide Metabolic Process Positive Regulation Of Non-canonical NF-kappaB Signal Transduction Regulation Of Lymphocyte Migration Positive Regulation Of Telomere Maintenance Negative Regulation Of Chromosome Organization Macromolecule Metabolic Process Negative Regulation Of Protein Localization To Lysosome Acetylcholine Receptor Activator Activity Axo-dendritic Transport	Positive Regulation Of Abscisic Acid-activated Signaling Pathway Peptide Modification
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