TDRKH and ZFP90

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TDRKH	ZFP90
Description		tudor and KH domain containing	ZFP90 zinc finger protein
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion P Granule Pi-body PiP-body	Nucleus
	Molecular Function	Nucleic Acid Binding RNA Binding Protein Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Male Meiotic Nuclear Division Spermatogenesis Fertilization Cell Differentiation P Granule Organization Regulatory NcRNA-mediated Gene Silencing PiRNA Processing	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription
Pathways		PIWI-interacting RNA (piRNA) biogenesis	Generic Transcription Pathway
Drugs
Diseases
GWAS		Asthma ( 30929738 31619474) Coronary artery disease ( 29212778 32469254) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Hemoglobin ( 32888494) Myocardial infarction ( 33532862)	Eosinophil count ( 32888494) Eosinophil percentage of white cells ( 32888494) HIV-1 viral setpoint ( 22174851) Response to antipsychotic treatment in schizophrenia (reasoning) ( 21107309) Systemic lupus erythematosus ( 27399966 28714469 33272962) Ulcerative colitis ( 21297633 23128233 28067908)
Interacting Genes		7 interacting genes: FAM25A FAM25C FAM25G LANCL2 SNRNP25 ZBTB34 ZFP90	23 interacting genes: ABI2 ATPAF2 BOLA2 BOLA2B CCNC CPNE7 ENKD1 EXOSC5 GCC1 GLYCTK GTPBP3 HOXC8 LMO1 LONRF1 MALSU1 MLH1 NEK6 PRKAB2 RUNX1T1 TBC1D22B TDRKH TEKT4 TRAPPC6A
Entrez ID		11022	146198
HPRD ID		15485	18729
Ensembl ID		ENSG00000182134	ENSG00000184939
Uniprot IDs		B4DJ68 Q9Y2W6	J3QKQ8 Q8TF47
PDB IDs		2DIQ 3FDR 5J39 6B57 6PI7
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Abscisic Acid-activated Signaling Pathway Peptide Modification	Iron-sulfur Cluster Assembly Complex [2Fe-2S] Cluster Assembly
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