UNC45A and PIBF1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		UNC45A	PIBF1
Description		unc-45 myosin chaperone A	progesterone immunomodulatory binding factor 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Golgi Apparatus Cytosol Nuclear Speck Perinuclear Region Of Cytoplasm	Extracellular Region Extracellular Space Nucleus Cytoplasm Centrosome Microtubule Organizing Center Cytoskeleton Centriolar Satellite Ciliary Basal Body
	Molecular Function	Protein Binding Cadherin Binding Hsp90 Protein Binding	Interleukin-4 Receptor Binding Protein Binding
	Biological Process	Protein Folding Muscle Organ Development Cell Differentiation	Immune System Process Mitotic Metaphase Chromosome Alignment Negative Regulation Of Prostaglandin Biosynthetic Process Negative Regulation Of Interleukin-12 Production Positive Regulation Of Interleukin-10 Production Negative Regulation Of Natural Killer Cell Activation Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Negative Regulation Of Tyrosine Phosphorylation Of STAT Protein Activation Of Janus Kinase Activity Cilium Assembly Protein Localization To Centrosome Mitotic Spindle Assembly Non-motile Cilium Assembly
Pathways
Drugs
Diseases
GWAS			Allergic disease (asthma, hay fever or eczema) ( 29083406) Blood pressure measurement (low sodium intervention) ( 24165912) Gout ( 32238385) Mean corpuscular hemoglobin ( 27863252 32888494) Mean corpuscular volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red blood cell count ( 32888494) Red cell distribution width ( 32888494) Waist circumference ( 28552196)
Interacting Genes		13 interacting genes: DIRAS2 HSP90AA1 HSP90AB1 KRTAP10-3 LMNA MARCHF10 MAX MEOX1 MEOX2 MID2 PIBF1 SMAD9 TEKT1	104 interacting genes: ALAS1 AMOTL2 ANKRD23 ANKRD28 APP ARHGAP45 ARID5A C7orf57 CARD10 CARD9 CATSPERT CBX8 CCDC13 CCDC136 CCDC138 CCHCR1 CDC37 CDK18 CEP135 CEP19 CEP63 CEP70 CFAP53 CWF19L2 DAXX DISC1 DMAP1 EFHC2 ENKD1 FAM161A FAM50B GMCL1 GOLGA2 GPKOW GRIPAP1 HAUS1 HOMEZ IGFN1 KANK2 KATNBL1 KIF9 KIFC3 KLHL2 LARP1B LMNB2 LZTS1 MAD1L1 MAP3K2 MCRS1 MDFI MFAP1 MORF4L1 MORF4L2 MTUS2 NEBL PHF1 PICK1 PKP2 PLEKHA7 POLDIP3 POU6F2 PPP1R18 PRPF18 PTPN21 RAB11FIP2 RBM11 RBM48 RNF151 RNF169 RSPH14 SCNM1 SLU7 SORBS3 SPATA18 STEEP1 SYT17 TAX1BP1 TCEA2 TFIP11 TNFAIP3 TNIP1 TNIP3 TP53BP2 TRAF2 TRAF5 TRIM27 TSGA10 TSHZ2 TSHZ3 UNC45A USP15 USP2 UTP14C XIAP ZBTB16 ZBTB4 ZC2HC1C ZFC3H1 ZFHX3 ZNF250 ZNF35 ZNF438 ZNF620 ZNF774
Entrez ID		55898	10464
HPRD ID		18070	06337
Ensembl ID		ENSG00000140553	ENSG00000083535
Uniprot IDs		Q9H3U1	Q8WXW3
PDB IDs		2DBA
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Biosynthetic Process Positive Regulation Of Metabolic Process Somite Specification Telomerase Holoenzyme Complex Assembly Positive Regulation Of Macromolecule Metabolic Process Nitric-oxide Synthase Regulator Activity Dendritic Growth Cone TPR Domain Binding Positive Regulation Of Macromolecule Biosynthetic Process Segment Specification Somite Development Chaperone-mediated Protein Complex Assembly Regulation Of Primary Metabolic Process Telomere Maintenance Via Telomerase DNA Polymerase Binding Axonal Growth Cone RNA-templated DNA Biosynthetic Process MHC Class II Protein Complex Binding Disordered Domain Specific Binding Telomere Maintenance Via Telomere Lengthening Protein Folding Chaperone Complex ATP-dependent Protein Folding Chaperone Positive Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Macromolecule Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Nitric Oxide Metabolic Process Tau Protein Binding Protein Localization To Cytoskeleton CTP Binding DATP Binding Cellular Response To Heat Protein Folding Chaperone Regulation Of Metabolic Process Embryonic Pattern Specification Regulation Of Nitric Oxide Biosynthetic Process Protein Localization To Organelle Regulation Of Protein Modification Process Regulation Of Nitric Oxide Metabolic Process Neurofibrillary Tangle Assembly UTP Binding Sulfonylurea Receptor Binding HSP90-CDC37 Chaperone Complex DNA Double-strand Break Attachment To Nuclear Envelope Structural Constituent Of Nuclear Lamina Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Myc-Max Complex Mad-Max Complex Negative Regulation Of Prostaglandin Biosynthetic Process DNA-binding Transcription Factor Activity	Protein Binding Identical Protein Binding Centrosome Cytoskeleton Nucleoplasm Spindle Pole Cytoplasm Centriole Regulation Of Innate Immune Response Regulation Of Canonical NF-kappaB Signal Transduction Nucleus Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signaling Pathway Positive Regulation Of Innate Immune Response Negative Regulation Of Nucleobase-containing Compound Metabolic Process Microtubule-based Process Zonula Adherens Maintenance Spliceosomal Complex Microtubule Binding Zinc Ion Binding Regulation Of Primary Metabolic Process Activation Of Innate Immune Response Regulation Of RNA Metabolic Process RNA Splicing CBM Complex Negative Regulation Of Canonical NF-kappaB Signal Transduction Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Defense Response Cell Projection Adherens Junction Maintenance Regulation Of DNA Repair NuA4 Histone Acetyltransferase Complex Regulation Of Immune Response Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of RNA Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway
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