DEFB103B and ODF4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		DEFB103B	ODF4
Description		defensin beta 103B	outer dense fiber of sperm tails 4
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Golgi Lumen	Membrane
	Molecular Function	Protein Binding CCR6 Chemokine Receptor Binding Chemoattractant Activity	Protein Binding
	Biological Process	Defense Response Killing Of Cells Of Another Organism Defense Response To Bacterium Defense Response To Gram-negative Bacterium Defense Response To Gram-positive Bacterium Positive Chemotaxis Killing By Host Of Symbiont Cells Cell Chemotaxis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Defense Response To Symbiont	Spermatogenesis Cell Differentiation
Pathways		Beta defensins Defensins
Drugs
Diseases
GWAS			Mean corpuscular hemoglobin concentration ( 29403010)
Interacting Genes		12 interacting genes: AQP6 B3GALT5 CCR6 EBP ERGIC3 ODF4 SCN3B SPATA31A7 SSMEM1 TMEM14B TMEM31 TMPRSS2	22 interacting genes: APP CACNG1 CD9 CDIPT CNIH3 DEFB103A DEFB103B EBP LAPTM4B MARCHF5 MEOX2 MS4A13 NINJ2 RUSF1 SACM1L SLC25A46 SLC38A7 TMEM119 TMEM239 TOMM6 TRARG1 YIPF6
Entrez ID		55894	146852
HPRD ID		05968	17658
Ensembl ID		ENSG00000177243	ENSG00000184650
Uniprot IDs		A0A894JZ42 P81534	C3TX97 Q2M2E3
PDB IDs		1KJ6
Enriched GO Terms of Interacting Partners?		Membrane PH-gated Chloride Channel Activity Nitrate Transmembrane Transporter Activity Nitrate Transmembrane Transport Isotype Switching To IgA Isotypes DN3 Thymocyte Differentiation Positive Regulation Of Flagellated Sperm Motility Involved In Capacitation C-8 Sterol Isomerase Activity Cholesterol-5,6-oxide Hydrolase Activity Cholestenol Delta-isomerase Activity Retrograde Transporter Complex, Golgi To ER Thymocyte Migration Entry Receptor-mediated Virion Attachment To Host Cell Cholesterol Biosynthetic Process Via Lathosterol Cholesterol Biosynthetic Process Via Desmosterol Steroid Delta-isomerase Activity DN2 Thymocyte Differentiation Viral Translation Transporter Complex Voltage-gated Sodium Channel Activity Involved In Cardiac Muscle Cell Action Potential	Membrane Chemoattractant Activity Positive Chemotaxis CCR6 Chemokine Receptor Binding Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel Defense Response To Gram-negative Bacterium
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