DEFB103B and SPATA31A7

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		DEFB103B	SPATA31A7
Description		defensin beta 103B	SPATA31 subfamily A member 7
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Golgi Lumen	Membrane
	Molecular Function	Protein Binding CCR6 Chemokine Receptor Binding Chemoattractant Activity	Protein Binding
	Biological Process	Defense Response Killing Of Cells Of Another Organism Defense Response To Bacterium Defense Response To Gram-negative Bacterium Defense Response To Gram-positive Bacterium Positive Chemotaxis Killing By Host Of Symbiont Cells Cell Chemotaxis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Defense Response To Symbiont	Spermatogenesis Cell Differentiation
Pathways		Beta defensins Defensins
Drugs
Diseases
GWAS
Interacting Genes		12 interacting genes: AQP6 B3GALT5 CCR6 EBP ERGIC3 ODF4 SCN3B SPATA31A7 SSMEM1 TMEM14B TMEM31 TMPRSS2	3 interacting genes: DEFB103A DEFB103B ODAM
Entrez ID		55894	26165
HPRD ID		05968	12954
Ensembl ID		ENSG00000177243	ENSG00000276040
Uniprot IDs		A0A894JZ42 P81534	Q8IWB4
PDB IDs		1KJ6
Enriched GO Terms of Interacting Partners?		Membrane PH-gated Chloride Channel Activity Nitrate Transmembrane Transporter Activity Nitrate Transmembrane Transport Isotype Switching To IgA Isotypes DN3 Thymocyte Differentiation Positive Regulation Of Flagellated Sperm Motility Involved In Capacitation C-8 Sterol Isomerase Activity Cholesterol-5,6-oxide Hydrolase Activity Cholestenol Delta-isomerase Activity Retrograde Transporter Complex, Golgi To ER Thymocyte Migration Entry Receptor-mediated Virion Attachment To Host Cell Cholesterol Biosynthetic Process Via Lathosterol Cholesterol Biosynthetic Process Via Desmosterol Steroid Delta-isomerase Activity DN2 Thymocyte Differentiation Viral Translation Transporter Complex Voltage-gated Sodium Channel Activity Involved In Cardiac Muscle Cell Action Potential	CCR6 Chemokine Receptor Binding Biological Process Involved In Interaction With Symbiont Chemoattractant Activity Killing By Host Of Symbiont Cells Positive Chemotaxis Defense Response To Gram-negative Bacterium Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Golgi Lumen Killing Of Cells Of Another Organism Defense Response To Gram-positive Bacterium Antimicrobial Humoral Response Cell Killing Cell Chemotaxis Defense Response Extracellular Space Humoral Immune Response Defense Response To Bacterium Chemotaxis Locomotion Positive Regulation Of Epithelial Cell Proliferation Involved In Wound Healing Supramolecular Fiber Response To Bacterium Extracellular Region Defense Response To Symbiont Defense Response To Other Organism Response To Stress Cell Migration Cell Motility Odontogenesis Of Dentin-containing Tooth Response To Other Organism Immune Response Cell Periphery Positive Regulation Of GTPase Activity Biomineral Tissue Development Odontogenesis Response To External Biotic Stimulus Positive Regulation Of Hydrolase Activity
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