PRKCSH and ARL4D

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PRKCSH	ARL4D
Description		PRKCSH beta subunit of glucosidase II	ARF like GTPase 4D
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Glucosidase II Complex Intracellular Membrane-bounded Organelle	Nucleus Nucleolus Cytoplasm Plasma Membrane Membrane
	Molecular Function	Protein Kinase C Binding Calcium Ion Binding Protein Binding Transmembrane Transporter Binding Metal Ion Binding Phosphoprotein Binding	Nucleotide Binding GTPase Activity Protein Binding GTP Binding
	Biological Process	Liver Development N-glycan Processing Intracellular Signal Transduction	Intracellular Protein Transport Protein Secretion Vesicle-mediated Transport
Pathways		Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) N-glycan trimming in the ER and Calnexin/Calreticulin cycle Advanced glycosylation endproduct receptor signaling Post-translational protein phosphorylation Calnexin/calreticulin cycle Maturation of spike protein Maturation of spike protein Regulation of CDH1 posttranslational processing and trafficking to plasma membrane
Drugs
Diseases		Polycystic liver disease
GWAS		Presence of antiphospholipid antibodies ( 27098658) Serum metabolite levels (CMS) ( 31636271)
Interacting Genes		11 interacting genes: ARL4D CANX ESR1 FXR1 GANAB GBA3 GET4 PTPRC RGS2 RPS6 VDR	22 interacting genes: APP ARL6IP1 CCDC102B CNPY4 CYTH2 DNAJA1 EIF2B1 EML4 EPRS1 MAPK8IP3 NDRG1 PGAM1 PRKCSH SMAD1 SMAD2 SMURF1 SNRPN TGFBR1 TLE1 TMEM230 UBR1 UNC119
Entrez ID		5589	379
HPRD ID		03518	02842
Ensembl ID		ENSG00000130175	ENSG00000175906
Uniprot IDs		B4DJQ5 K7ELL7 P14314	P49703
PDB IDs		8D43 8EMR
Enriched GO Terms of Interacting Partners?		Maternal Process Involved In Female Pregnancy Mammary Gland Branching Involved In Pregnancy Nucleolus Branching Involved In Mammary Gland Duct Morphogenesis Nuclear Steroid Receptor Activity Hydrolase Activity, Hydrolyzing O-glycosyl Compounds Membrane RNA Binding ERAD Pathway Presynapse Negative Regulation Of Nucleobase-containing Compound Metabolic Process Nuclear Estrogen Receptor Activity Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of RNA Metabolic Process Positive Regulation Of Cell Population Proliferation Transcription Preinitiation Complex Assembly TFIIB-class Transcription Factor Binding Prostate Epithelial Cord Elongation Transcription Coregulator Binding Regulation Of MiRNA Transcription Positive Regulation Of Catalytic Activity Nuclear Receptor-mediated Signaling Pathway Positive Regulation Of Nitric-oxide Synthase Activity Regulation Of MiRNA Metabolic Process Developmental Process Involved In Reproduction Regulation Of Intracellular Signal Transduction Negative Regulation Of Intracellular Signal Transduction Steroid Hormone Receptor Signaling Pathway Regulation Of Inflammatory Response Negative Regulation Of Biosynthetic Process Nuclear Receptor-mediated Steroid Hormone Signaling Pathway Nuclear Receptor Activity Antral Ovarian Follicle Growth Negative Regulation Of Gene Expression Negative Regulation Of Interleukin-4-mediated Signaling Pathway Positive Regulation Of Hematopoietic Stem Cell Migration Regulation Of Cell Differentiation DN2 Thymocyte Differentiation Plasma Membrane Raft Distribution Cytoplasmic Side Of Plasma Membrane Regulation Of Multicellular Organismal Development Positive Regulation Of Cell Differentiation Response To Alcohol Membrane Microdomain Negative Regulation Of Cell Adhesion Involved In Substrate-bound Cell Migration Negative Regulation Of Glycine Import Across Plasma Membrane Adenylate Cyclase Inhibitor Activity Regulation Of Adenylate Cyclase-inhibiting Adrenergic Receptor Signaling Pathway Negative Regulation Of Transmembrane Transport Cytoplasmic Ribonucleoprotein Granule	I-SMAD Binding Homomeric SMAD Protein Complex SMAD Protein Complex SMAD Binding Trophoblast Cell Migration Heteromeric SMAD Protein Complex Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway Co-SMAD Binding Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway Primary MiRNA Processing Axo-dendritic Transport Transforming Growth Factor Beta Receptor Binding Transforming Growth Factor Beta Receptor Signaling Pathway Low-density Lipoprotein Particle Receptor Binding Response To Growth Factor Protein Serine/threonine Kinase Binding Cytosol Cytoplasm Ubiquitin Protein Ligase Binding SMAD Protein Signal Transduction Embryonic Cranial Skeleton Morphogenesis Activin Receptor Signaling Pathway Response To Cholesterol R-SMAD Binding Growth Cone Regulation Of JNK Cascade MiRNA Processing Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Proline-tRNA Ligase Activity Prolyl-tRNA Aminoacylation Ureteric Bud Development Engulfment Of Target By Autophagosome Transport Along Microtubule
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