PRKD1 and HS3ST1

		PRKD1	HS3ST1
Description		protein kinase D1	heparan sulfate-glucosamine 3-sulfotransferase 1
Image		No pdb structure
GO Annotations	Cellular Component	Autophagosome Membrane Nucleus Cytoplasm Golgi Apparatus Trans-Golgi Network Cytosol Plasma Membrane Cell-cell Junction Cell Cortex Membrane Z Disc Perinuclear Region Of Cytoplasm	Golgi Apparatus Golgi Lumen
	Molecular Function	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Diacylglycerol-dependent Serine/threonine Kinase Activity Protein Kinase C Binding Protein Binding ATP Binding Zinc Ion Binding Kinase Activity Transferase Activity Heat Shock Protein Binding Identical Protein Binding Metal Ion Binding Protein Serine Kinase Activity Phosphatidylinositol 3-kinase Activator Activity	Sulfotransferase Activity [heparan Sulfate]-glucosamine 3-sulfotransferase Activity Transferase Activity
	Biological Process	Angiogenesis Positive Regulation Of Endothelial Cell Proliferation Immune System Process Apoptotic Process Inflammatory Response Golgi Organization Signal Transduction Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Integrin-mediated Signaling Pathway Nervous System Development Positive Regulation Of Autophagy Positive Regulation Of Endothelial Cell Migration Positive Regulation Of Gene Expression Regulation Of Keratinocyte Proliferation Positive Regulation Of Neuron Projection Development Regulation Of Skeletal Muscle Contraction By Modulation Of Calcium Ion Sensitivity Of Myofibril Sphingolipid Biosynthetic Process Cell Differentiation Cellular Response To Amino Acid Starvation Cellular Response To Oxidative Stress Intracellular Signal Transduction Cellular Response To Vascular Endothelial Growth Factor Stimulus Positive Regulation Of Protein Import Into Nucleus Positive Regulation Of Canonical NF-kappaB Signal Transduction Positive Regulation Of Blood Vessel Endothelial Cell Migration Cell-cell Adhesion Mediated By Cadherin Innate Immune Response Positive Regulation Of Osteoblast Differentiation Positive Regulation Of Angiogenesis Positive Regulation Of Cell Size Negative Regulation Of Endocytosis Positive Regulation Of Transcription By RNA Polymerase II Protein Autophosphorylation Positive Regulation Of Protein Export From Nucleus Vascular Endothelial Growth Factor Receptor Signaling Pathway Golgi Vesicle Transport Defense Response To Gram-negative Bacterium Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of Sarcomere Organization Transepithelial Transport Cellular Response To Hydroperoxide Response To Norepinephrine Cellular Response To Norepinephrine Stimulus Positive Regulation Of Peptide Hormone Secretion Positive Regulation Of NLRP3 Inflammasome Complex Assembly Cellular Response To Angiotensin Cellular Response To Phorbol 13-acetate 12-myristate Cellular Response To Endothelin Positive Regulation Of Endothelial Cell Chemotaxis Regulation Of Integrin-mediated Signaling Pathway	Glycosaminoglycan Biosynthetic Process Heparan Sulfate Proteoglycan Biosynthetic Process
Pathways		Sphingolipid de novo biosynthesis	HS-GAG biosynthesis
Drugs		Bryostatin 1 Fostamatinib	Adenosine 3',5'-diphosphate
Diseases
GWAS		Academic attainment (English) ( 33594131) Adult body size ( 32376654) BMI (adjusted for smoking behaviour) ( 28443625) Body mass index ( 20935630 23669352 25673413 28552196 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Body mass index in physically active individuals ( 28448500) Body size at age 10 ( 32376654) California verbal learning test score ( 31596458) Carotid plaque burden ( 28282560) Cerebral amyloid deposition in APOEe4 non-carriers (PET imaging) ( 26252872) Childhood body mass index ( 26604143) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Daytime nap ( 33568662) General cognitive ability ( 29844566) General risk tolerance (MTAG) ( 30643258) Hip circumference ( 28552196) Household income (MTAG) ( 31844048) IgM levels ( 28628107) Intelligence (MTAG) ( 29326435) Neurociticism ( 29500382) Obesity-related traits ( 23251661) Schizophrenia ( 30285260 29483656 25056061 34099189) Spatial processing ( 31596458) Systolic blood pressure ( 30224653) Type 2 diabetes ( 30130595) Urinary sodium excretion ( 31409800) Waist circumference ( 28552196 25673412) Weight ( 28552196)	Alzheimer's disease ( 34099642) Alzheimer's disease (late onset) ( 24162737 30617256) Ankylosing spondylitis ( 30946743) Daytime sleep phenotypes ( 27126917) Exploratory eye movement dysfunction in schizophrenia (cognitive search score) ( 26242244) Intraocular pressure ( 30591961) Nonalcoholic fatty liver disease ( 22719876) Photic sneeze reflex ( 27182965 30899065) Response to ziprazidone in schizophrenia ( 29503163) Rheumatoid arthritis ( 30891314)
Interacting Genes		33 interacting genes: ABL1 ADAP1 AKAP13 BTK C1QBP COPS2 COPS5 COPS7A EGFR EPAS1 HDAC5 HDAC7 IBTK IGF1R JUN KIDINS220 MAPK8 MAPK9 MT2A NOS1 PLCG1 PLCG2 PPP1R14A PRKCE PRKCH RACK1 SPRY2 SRC SYK TFAP2A TP53 USP28 YWHAQ	1 interacting genes: APP
Entrez ID		5587	9957
HPRD ID		05668	04455
Ensembl ID		ENSG00000184304	ENSG00000002587
Uniprot IDs		F8WBA3 Q15139	O14792
PDB IDs			1ZRH
Enriched GO Terms of Interacting Partners?		Intracellular Signaling Cassette Fc Receptor Signaling Pathway Intracellular Signal Transduction Fc-epsilon Receptor Signaling Pathway Regulation Of Programmed Cell Death Positive Regulation Of Protein-containing Complex Assembly Cytosol Positive Regulation Of Cell Migration Regulation Of Apoptotic Process Positive Regulation Of Cell Motility Positive Regulation Of Locomotion Regulation Of Protein Metabolic Process Regulation Of Protein Modification Process Phosphorylation Immune Response-regulating Cell Surface Receptor Signaling Pathway Positive Regulation Of Signal Transduction Enzyme Binding Signal Transduction Regulation Of Protein-containing Complex Assembly Negative Regulation Of Metabolic Process Negative Regulation Of Programmed Cell Death MAPK Cascade Positive Regulation Of Cell Communication Positive Regulation Of Signaling Protein-containing Complex Negative Regulation Of Macromolecule Metabolic Process Protein Phosphorylation Regulation Of Post-translational Protein Modification Positive Regulation Of Intracellular Signal Transduction Kinase Activity Protein Kinase C Binding Response To Lipid Regulation Of Cell Migration Regulation Of Multicellular Organismal Process Positive Regulation Of Epithelial Cell Migration Protein Kinase Activity Cell Activation Regulation Of Protein Neddylation Positive Regulation Of Cellular Component Biogenesis Regulation Of Cell Motility Cellular Response To Growth Factor Stimulus Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Cellular Response To Oxygen-containing Compound Positive Regulation Of Metabolic Process Regulation Of Primary Metabolic Process Immune Response-regulating Signaling Pathway Regulation Of Locomotion Positive Regulation Of Programmed Cell Death	Response To Norepinephrine Cellular Response To Norepinephrine Stimulus Cellular Response To Catecholamine Stimulus Response To Catecholamine Defense Response To Gram-negative Bacterium Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Calcium Ion Transmembrane Transport Regulation Of Response To Calcium Ion Calcium-mediated Signaling Positive Regulation Of Chemotaxis Amylin Binding Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Supramolecular Fiber Organization Regulation Of Protein Localization To Nucleus Regulation Of Skeletal Muscle Contraction By Modulation Of Calcium Ion Sensitivity Of Myofibril Regulation Of Chemotaxis Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Positive Regulation Of Establishment Of Protein Localization Response To Growth Factor Endosome To Plasma Membrane Transport Vesicle Cellular Response To Growth Factor Stimulus Positive Regulation Of Endothelin Production Growth Cone Filopodium Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Regulation Of Monoatomic Ion Transmembrane Transport Defense Response To Bacterium Regulation Of Calcium Ion Transport Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Regulation Of Monoatomic Cation Transmembrane Transport Regulation Of Endocytosis Positive Regulation Of Protein Transport Regulation Of Metal Ion Transport Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Regulation Of Monoatomic Ion Transport Axon Midline Choice Point Recognition Regulation Of Supramolecular Fiber Organization Positive Regulation Of Amyloid Fibril Formation Response To Bacterium Growth Factor Receptor Binding Main Axon
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?