USE1 and SLC71A2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		USE1	SLC71A2
Description		unconventional SNARE in the ER 1	solute carrier family 71 member 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lysosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane COPI-coated Vesicle SNARE Complex	Membrane
	Molecular Function	SNAP Receptor Activity Protein Binding	Protein Binding Transmembrane Transporter Activity
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Endoplasmic Reticulum Organization Lysosomal Transport Protein Transport Vesicle-mediated Transport Protein Catabolic Process Secretion By Cell Regulation Of ER To Golgi Vesicle-mediated Transport Membrane Fusion Endoplasmic Reticulum Tubular Network Organization	Transmembrane Transport
Pathways		COPI-dependent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Night sleep phenotypes ( 27126917)
Interacting Genes		18 interacting genes: APOL2 APP AQP6 BSCL2 CALN1 CCDC70 CCM2L CREB3 EBP JAGN1 LMNA MEOX2 SCN3B SLC71A2 STX1A STX4 TMEM86B TRIM27	75 interacting genes: ADIPOQ AGPAT3 AGPAT4 ARL6IP1 ARLN ATP13A1 BNIP3 C14orf180 CCL4L2 CFHR5 CLDN4 CMTM3 COMT CSGALNACT2 CTSA CYB5B CYBC1 DEFB127 DNAJC30 EMC6 ERG28 FKBP8 FMO1 FUNDC2 GIMAP1 GOSR2 GRM2 KTN1 LAT LEPROTL1 LPCAT2 LRP10 MGLL MS4A1 NAT8 ORMDL1 PEX16 PKMYT1 PRRT2 RNF24 SACM1L SCD SERP1 SERP2 SLC25A46 SLC39A9 SLC66A2 SMAGP STX3 TECR THSD7B TIMMDC1 TMBIM6 TMEM119 TMEM167B TMEM176A TMEM19 TMEM208 TMEM229B TMEM239 TMEM31 TMX2 TPRG1 TRARG1 TREX1 TSNARE1 UBE2J1 UNC50 USE1 YIPF1 YIPF2 YIPF4 YIPF6 ZDHHC24 ZFPL1
Entrez ID		55850	84641
HPRD ID		11299	07869
Ensembl ID		ENSG00000053501	ENSG00000148110
Uniprot IDs		Q9NZ43	Q5SR56
PDB IDs
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Amyloid-beta Complex Lipoprotein Metabolic Process Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Positive Regulation Of Excitatory Postsynaptic Potential Regulation Of Establishment Of Protein Localization Regulation Of Chemotaxis Positive Regulation Of Chemotaxis Amylin Binding Positive Regulation Of Toll Signaling Pathway Defense Response To Fungus Positive Regulation Of Synaptic Transmission Response To Fungus Regulation Of Protein Localization Lipoprotein Particle Regulation Of Protein Transport Positive Regulation Of Monocyte Chemotaxis Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Transport Positive Regulation Of Protein Import Modulation Of Excitatory Postsynaptic Potential Regulation Of Monocyte Chemotaxis Identical Protein Binding PH-gated Chloride Channel Activity Nitrate Transmembrane Transporter Activity Nitrate Transmembrane Transport DNA Double-strand Break Attachment To Nuclear Envelope Nuclear Membrane Structural Constituent Of Nuclear Lamina Protein Sumoylation SNARE Complex Regulation Of Insulin Secretion Insulin Secretion Positive Regulation Of Regulated Secretory Pathway Regulation Of Peptide Hormone Secretion SNARE Complex Assembly SNAP Receptor Activity Myosin Head/neck Binding SNARE Binding Vesicle Docking Exocytosis Positive Regulation Of Eosinophil Degranulation Sphingomyelin Phosphodiesterase Activator Activity Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Storage Vacuole Endoplasmic Reticulum Membrane Positive Regulation Of Deacetylase Activity	Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Endomembrane System Membrane Organization Organelle Membrane Fusion Vesicle Fusion Membrane Fusion Golgi Trans Cisterna Golgi Medial Cisterna Vesicle-mediated Transport Lysophosphatidic Acid Acyltransferase Activity Exocytic Insertion Of Neurotransmitter Receptor To Postsynaptic Membrane SNAP Receptor Activity Organelle Fusion SNARE Complex Golgi Apparatus 1-acylglycerol-3-phosphate O-acyltransferase Activity Cellular Localization Golgi Membrane Trans-Golgi Network Establishment Of Protein Localization To Membrane Secretion By Cell Protein Binding Establishment Of Protein Localization Lipid Biosynthetic Process Acyltransferase Activity
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