RIOK2 and TSTA3

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		RIOK2	TSTA3
Gene Name		RIO kinase 2	tissue specific transplantation antigen P35B
Image		No pdb structure
Gene Ontology Annotations	Cellular Component		Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Protein Serine/threonine Kinase Activity ATP Binding	Electron Carrier Activity Isomerase Activity GDP-4-dehydro-D-rhamnose Reductase Activity GDP-L-fucose Synthase Activity Coenzyme Binding
	Biological Process	Protein Phosphorylation	Leukocyte Cell-cell Adhesion GDP-mannose Metabolic Process Cytolysis 'de Novo' GDP-L-fucose Biosynthetic Process Oxidation-reduction Process
Pathways
Drugs			NADH
Diseases
GWAS			Rhegmatogenous retinal detachment ( 23585552)
Protein-Protein Interactions		6 interactors: APP CSNK2A1 RELA RPRD1A SMAD3 TSTA3	3 interactors: ID2 NEDD4 RIOK2
Entrez ID		55781	7264
HPRD ID		10193	00654
Ensembl ID		ENSG00000058729	ENSG00000104522
Uniprot IDs		Q9BVS4	Q13630
PDB IDs			4B8W 4B8Z 4BKP 4E5Y
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Protein Catabolic Process Positive Regulation Of Chondrocyte Differentiation Negative Regulation Of Protein Metabolic Process Positive Regulation Of Cartilage Development Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Regulation Of Endopeptidase Activity Regulation Of Protein Catabolic Process Regulation Of Peptidase Activity Regulation Of Mitotic Cell Cycle Positive Regulation Of Protein Metabolic Process Regulation Of Chondrocyte Differentiation Regulation Of Cartilage Development Positive Regulation Of Transforming Growth Factor Beta3 Production Acetaldehyde Metabolic Process Regulation Of Growth Regulation Of Proteolysis Response To External Stimulus Regulation Of Transcription From RNA Polymerase II Promoter Synaptic Growth At Neuromuscular Junction Positive Regulation Of Schwann Cell Differentiation 'de Novo' GDP-L-fucose Biosynthetic Process Positive Regulation Of Peptidase Activity Liver Development Positive Regulation Of Wnt Signaling Pathway Collateral Sprouting In Absence Of Injury Regulation Of Schwann Cell Differentiation Evasion Or Tolerance Of Host Defenses By Virus GDP-L-fucose Metabolic Process Negative Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Cell Development Regulation Of Protein Metabolic Process Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway Positive Regulation Of Extracellular Matrix Assembly Response To Cobalamin Dephosphorylation Of RNA Polymerase II C-terminal Domain Regulation Of Transcription, DNA-templated Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Apoptotic Process Intracellular Receptor Signaling Pathway Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Programmed Cell Death Regulation Of RNA Biosynthetic Process Regulation Of Cell Cycle Regulation Of Cysteine-type Endopeptidase Activity Regulation Of RNA Metabolic Process Regulation Of Extracellular Matrix Assembly Collateral Sprouting Axon Midline Choice Point Recognition Apoptotic Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Transmission Of Virus Development Involved In Symbiotic Interaction Positive Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Heart Morphogenesis Bundle Of His Development Endodermal Digestive Tract Morphogenesis Response To Metal Ion Epithelial Cell Differentiation Involved In Mammary Gland Alveolus Development Response To Light Stimulus Progesterone Receptor Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Lymphocyte Activation Negative Regulation Of B Cell Differentiation Membranous Septum Morphogenesis Glucocorticoid Receptor Signaling Pathway Response To Radiation Locomotor Rhythm Response To Inorganic Substance Positive Regulation Of Astrocyte Differentiation Leukocyte Activation Heart Development Positive Regulation Of Macrophage Differentiation Protein Targeting To Lysosome Negative Regulation Of Sodium Ion Transport Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Neuron Differentiation Cardiac Conduction System Development Protein Localization To Lysosome Enucleate Erythrocyte Differentiation Cellular Response To Lithium Ion Circadian Behavior Peyer's Patch Development Rhythmic Behavior Cell Activation Receptor Catabolic Process Positive Regulation Of Erythrocyte Differentiation Natural Killer Cell Differentiation Regulation Of Neurogenesis Negative Regulation Of Oligodendrocyte Differentiation Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Protein Targeting To Vacuole Mammary Gland Epithelial Cell Proliferation Entrainment Of Circadian Clock By Photoperiod Mammary Gland Epithelial Cell Differentiation Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Negative Regulation Of Transcription From RNA Polymerase II Promoter Establishment Of Protein Localization To Vacuole Photoperiodism Entrainment Of Circadian Clock
Tagcloud ?		checkpoint chemosensitivity creates drive drives drosophila exit feedforward glial glioblastoma glioblastomas imply incurable kinome maintains melanogaster neoplastic oncogenesis opportunities orthologs overexpressed pi3k riok1 rpl11 rtk screen screens uncovered
Tagcloud (Difference) ?		checkpoint chemosensitivity creates drive drives drosophila exit feedforward glial glioblastoma glioblastomas imply incurable kinome maintains melanogaster neoplastic oncogenesis opportunities orthologs overexpressed pi3k riok1 rpl11 rtk screen screens uncovered
Tagcloud (Intersection) ?