GFUS

Name	GDP-L-fucose synthase
Structure
Interactors	4 interactors: ID2 NEDD4 RIOK2 UBC
GO Annotations	Cellular Component	Cytosol Extracellular Exosome
	Molecular Function	Catalytic Activity Protein Binding Electron Transfer Activity Oxidoreductase Activity Isomerase Activity GDP-4-dehydro-D-rhamnose Reductase Activity Identical Protein Binding GDP-mannose 3,5-epimerase Activity GDP-L-fucose Synthase Activity
	Biological Process	T Cell Mediated Cytotoxicity Leukocyte Cell-cell Adhesion Nucleotide-sugar Biosynthetic Process Positive Regulation Of Endothelial Cell Migration GDP-mannose Metabolic Process 'de Novo' GDP-L-fucose Biosynthetic Process Positive Regulation Of Endothelial Cell-matrix Adhesion Via Fibronectin
Pathways	GDP-fucose biosynthesis
Drugs	NADH
GWAS	No GWAS studies recorded
Entrez ID	7264
HPRD ID	00654
Ensembl ID	ENSG00000104522
Uniprot IDs	A0A140VKC8 Q13630
PDB IDs	4B8W 4B8Z 4BKP 4BL5 4E5Y
GO Terms Enriched among Interactors ?	Positive Regulation Of Nucleocytoplasmic Transport Formation Of Structure Involved In A Symbiotic Process Positive Regulation Of Ribosomal Small Subunit Export From Nucleus Regulation Of Nucleocytoplasmic Transport Transmembrane Transporter Binding Channel Inhibitor Activity Positive Regulation Of Intracellular Transport Endodermal Digestive Tract Morphogenesis Thigmotaxis Phosphothreonine Residue Binding Negative Regulation Of Dopaminergic Neuron Differentiation Bundle Of His Development Epithelial Cell Differentiation Involved In Mammary Gland Alveolus Development Nuclear Receptor-mediated Glucocorticoid Signaling Pathway Nuclear Receptor-mediated Corticosteroid Signaling Pathway Phosphoserine Residue Binding Regulation Of Intracellular Transport Beta-2 Adrenergic Receptor Binding Negative Regulation Of Potassium Ion Export Across Plasma Membrane Negative Regulation Of B Cell Differentiation Peyer's Patch Development Locomotor Rhythm Tube Morphogenesis Nucleoplasm Enucleate Erythrocyte Differentiation Regulation Of Dopaminergic Neuron Differentiation Regulation Of Mitotic Cell Cycle Phase Transition Mucosa-associated Lymphoid Tissue Development Response To Metal Ion Response To Light Stimulus Membranous Septum Morphogenesis Positive Regulation Of Astrocyte Differentiation Sodium Channel Inhibitor Activity Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Potassium Ion Export Across Plasma Membrane Progesterone Receptor Signaling Pathway Potassium Channel Inhibitor Activity Positive Regulation Of RRNA Processing Preribosome, Small Subunit Precursor Ventricular Cardiac Muscle Tissue Development Negative Regulation Of Oligodendrocyte Differentiation Endocardial Cushion Development Protein Modification Process Negative Regulation Of Sodium Ion Transport Regulation Of RRNA Processing Response To Lithium Ion Positive Regulation Of Macrophage Differentiation Embryonic Digestive Tract Morphogenesis Mammary Gland Epithelial Cell Differentiation Cellular Response To Lithium Ion