RIOK2

Description		RIO kinase 2
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Preribosome, Small Subunit Precursor
	Molecular Function	Nucleotide Binding Catalytic Activity Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Metal Ion Binding Protein Serine Kinase Activity
	Biological Process	Regulation Of Mitotic Metaphase/anaphase Transition Maturation Of SSU-rRNA Ribosome Biogenesis Ribosomal Small Subunit Biogenesis Protein Autophosphorylation Positive Regulation Of Ribosomal Small Subunit Export From Nucleus Positive Regulation Of RRNA Processing
Pathways		Major pathway of rRNA processing in the nucleolus and cytosol
Drugs		Fostamatinib
Diseases
GWAS		Chronic mountain sickness ( 31417607) Metabolite levels ( 23823483)
Interacting Genes		7 interacting genes: APP CSNK2A1 GFUS PRDM16 RELA RPRD1A SMAD3
Entrez ID		55781
HPRD ID		10193
Ensembl ID		ENSG00000058729
Uniprot IDs		Q9BVS4
PDB IDs		5DHF 6FDM 6FDN 6FDO 6G18 6G51 6HK6 7VBT 7WU0 9F81
Enriched GO Terms of Interacting Partners?		Negative Regulation Of MiRNA Transcription Positive Regulation Of Interleukin-1 Beta Production Positive Regulation Of Interleukin-1 Production Regulation Of MiRNA Transcription Regulation Of MiRNA Metabolic Process Regulation Of Protein Catabolic Process Identical Protein Binding Regulation Of Interleukin-1 Beta Production Regulation Of Interleukin-1 Production Negative Regulation Of Protein Catabolic Process DNA-binding Transcription Factor Binding Response To Angiotensin Positive Regulation Of Amyloid Precursor Protein Catabolic Process Positive Regulation Of Nitric Oxide Biosynthetic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Signal Transduction Involved In Regulation Of Gene Expression Positive Regulation Of Nitric Oxide Metabolic Process Transcription Cis-regulatory Region Binding Cellular Response To Growth Factor Stimulus Regulation Of Amyloid Precursor Protein Catabolic Process Transcription Coactivator Binding Regulation Of Wnt Signaling Pathway Response To Growth Factor Positive Regulation Of MiRNA Transcription Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Nitric Oxide Biosynthetic Process Enzyme Binding Regulation Of Response To Calcium Ion Negative Regulation Of Transcription By RNA Polymerase II Amylin Binding Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Non-canonical NF-kappaB Signal Transduction Regulation Of Apoptotic Signaling Pathway Regulation Of Nitric Oxide Metabolic Process Negative Regulation Of Catabolic Process Positive Regulation Of Cell-matrix Adhesion Negative Regulation Of Lung Blood Pressure Positive Regulation Of MiRNA Metabolic Process Nuclear Mineralocorticoid Receptor Binding GDP-L-fucose Synthase Activity GDP-4-dehydro-D-rhamnose Reductase Activity GDP-mannose 3,5-epimerase Activity Regulation Of Inflammatory Response Response To Interleukin-1 DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Chromatin DNA Binding Response To CAMP Negative Regulation Of Gene Expression Negative Regulation Of Macromolecule Biosynthetic Process
Tagcloud ?