MBD5 and KIAA1549

Number of citations of the paper that reports this interaction (PMID 12421765)
28

Data Source:
HPRD (two hybrid)

		MBD5	KIAA1549
Gene Name		methyl-CpG binding domain protein 5	KIAA1549
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Chromocenter Extracellular Vesicular Exosome	Integral Component Of Membrane
	Molecular Function	DNA Binding Chromatin Binding
	Biological Process	Nervous System Development Regulation Of Multicellular Organism Growth Glucose Homeostasis Single-organism Behavior Positive Regulation Of Growth Hormone Receptor Signaling Pathway
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		2 interactors: APC KIAA1549	10 interactors: CADPS CDC73 DST GNE ITSN2 LGALS4 MBD5 MYO5B SOD2 ZBTB16
Entrez ID		55777	57670
HPRD ID		11295	13873
Ensembl ID		ENSG00000204406	ENSG00000122778
Uniprot IDs		E9PHH0 Q9P267	Q9HCM3
PDB IDs
Enriched GO Terms of Interacting Partners?		Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process Negative Regulation Of Odontogenesis Metaphase/anaphase Transition Of Mitotic Cell Cycle Canonical Wnt Signaling Pathway Involved In Negative Regulation Of Apoptotic Process Negative Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Positive Regulation Of Microtubule Polymerization Positive Regulation Of Pseudopodium Assembly Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Regulation Of Attachment Of Spindle Microtubules To Kinetochore Muscle Cell Cellular Homeostasis Regulation Of Microtubule Polymerization Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Regulation Of Odontogenesis Negative Regulation Of Microtubule Depolymerization Mitotic Spindle Assembly Checkpoint Spindle Assembly Checkpoint Cytoplasmic Microtubule Organization Mitotic Spindle Checkpoint Mitotic Cytokinesis Negative Regulation Of Chromosome Segregation Negative Regulation Of Microtubule Polymerization Or Depolymerization Regulation Of Mitotic Sister Chromatid Separation Proximal/distal Pattern Formation Spindle Checkpoint Negative Regulation Of Mitotic Nuclear Division Tight Junction Assembly Regulation Of Mitotic Metaphase/anaphase Transition Thymus Development Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process T Cell Differentiation In Thymus Regulation Of Osteoclast Differentiation Somatic Stem Cell Maintenance Regulation Of Microtubule Polymerization Or Depolymerization Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Epithelial Cell Differentiation Apical Junction Assembly Execution Phase Of Apoptosis Negative Regulation Of Cellular Protein Catabolic Process Regulation Of Chromosome Segregation Negative Regulation Of Cell Division Negative Regulation Of Chromosome Organization Negative Regulation Of Protein Complex Disassembly Canonical Wnt Signaling Pathway Hair Follicle Development Hair Cycle Process Cytokinesis Regulation Of Protein Depolymerization Hair Cycle	Negative Regulation Of Fibroblast Proliferation Erythrophore Differentiation Age-dependent Response To Reactive Oxygen Species Vasodilation By Acetylcholine Involved In Regulation Of Systemic Arterial Blood Pressure Negative Regulation Of Myeloid Cell Differentiation Regulation Of Fibroblast Proliferation N-acetylglucosamine Biosynthetic Process Positive Regulation Of Growth Hormone Receptor Signaling Pathway Response To Silicon Dioxide Response To Magnetism Regulation Of Fat Cell Differentiation Catecholamine Secretion Regulation Of Growth Hormone Receptor Signaling Pathway Age-dependent Response To Oxidative Stress Positive Regulation Of NK T Cell Differentiation Detection Of Oxygen Negative Regulation Of Cell Proliferation Regulation Of Myeloid Cell Differentiation Male Germ-line Stem Cell Asymmetric Division Response To Selenium Ion Endosome Localization Negative Regulation Of Cell Differentiation Oxygen Homeostasis Cellular Response To Ethanol N-acetylneuraminate Metabolic Process Histone H2B Ubiquitination Hydrogen Peroxide Biosynthetic Process Synaptic Vesicle Priming Response To Isolation Stress
Tagcloud ?		2q23 abnormal advance autistic behavioral behaviors carriers carry causal confirm cpg craniofacial delay deletion disability distinctive emergence gt hallmark haploinsufficiency intellectual microdeletion motor neurite outgrowth phenotype phenotypes recapitulates uncovered	10q 3q26 6q23 7q34 9q astrocytoma chek2 dnt dysembryoplastic encompassed fam131b fibrillary ganglioglioma gliomas lggs mbs medulloblastomas neuroepithelial nf1 nf2 philadelphia pilocytic q10 qki refine sanger thr599dup tier v600e
Tagcloud (Difference) ?		2q23 abnormal advance autistic behavioral behaviors carriers carry causal confirm cpg craniofacial delay deletion disability distinctive emergence gt hallmark haploinsufficiency intellectual microdeletion motor neurite outgrowth phenotype phenotypes recapitulates uncovered	10q 3q26 6q23 7q34 9q astrocytoma chek2 dnt dysembryoplastic encompassed fam131b fibrillary ganglioglioma gliomas lggs mbs medulloblastomas neuroepithelial nf1 nf2 philadelphia pilocytic q10 qki refine sanger thr599dup tier v600e
Tagcloud (Intersection) ?