ENAH and XIRP1

Number of citations of the paper that reports this interaction (PubMedID 16631741)
0

Data Source:
BioGRID (two hybrid)

		ENAH	XIRP1
Description		ENAH actin regulator	xin actin binding repeat containing 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Focal Adhesion Lamellipodium Filopodium Cell Projection Synapse Anchoring Junction Postsynapse GABA-ergic Synapse	Stress Fiber Adherens Junction Focal Adhesion Cell Junction Desmosome Anchoring Junction
	Molecular Function	Actin Binding Protein Binding Profilin Binding SH3 Domain Binding Protein Domain Specific Binding WW Domain Binding	RNA Binding Actin Binding Protein Binding Actin Filament Binding
	Biological Process	Axon Guidance Actin Polymerization Or Depolymerization Actin Polymerization-dependent Cell Motility Postsynaptic Cytoskeleton Organization	Actin Filament Organization Intracellular Protein Localization Myoblast Differentiation Involved In Skeletal Muscle Regeneration Satellite Cell Activation Involved In Skeletal Muscle Regeneration Actin Cytoskeleton Organization Negative Regulation Of Protein Binding
Pathways		Generation of second messenger molecules Signaling by ROBO receptors Signaling by ROBO receptors
Drugs
Diseases
GWAS		Delirium ( 29631748) Depression in smokers ( 30219690) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Neuroticism ( 27067015) Obesity-related traits ( 23251661)	Apolipoprotein A1 levels ( 32203549) Cognitive decline rate in late mild cognitive impairment ( 26252872) Daytime sleep phenotypes ( 27126917) Social communication problems ( 24564958)
Interacting Genes		27 interacting genes: ABI1 ABI2 ABI3 ABL1 APBB1 BAIAP2 DNMBP EVL FAT1 FYB1 GPHN HMGB1 KLHDC3 MAPK1 PFN1 PRPF40A RAC1 RAD51 ROBO4 SPTA1 TERF2IP TES VASP WAS XIRP1 YAP1 ZYX	9 interacting genes: ACTA1 ENAH EVL FLNC NEB NEBL RNF10 SH3RF1 VASP
Entrez ID		55740	165904
HPRD ID		12360	16727
Ensembl ID		ENSG00000154380	ENSG00000168334
Uniprot IDs		A0A097PIC4 A0A097PID1 A0A4D6J698 Q8N8S7	Q702N8
PDB IDs		2HO2 2IYB 2XQN 4MY6 5N91 5N9C 5N9P 5NAJ 5NBF 5NBX 5NC2 5NC7 5NCF 5NCG 5NCP 5ND0 5NDU 5NEG 6RCF 6RCJ 6RD2 6XVT 6XXR 7A5M 7AKI 7LXE 9C66
Enriched GO Terms of Interacting Partners?		Actin Filament Organization Actin Polymerization Or Depolymerization Supramolecular Fiber Organization Lamellipodium Cytoskeleton Proline-rich Region Binding Regulation Of Actin Filament Organization Regulation Of Actin Cytoskeleton Organization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Regulation Of Supramolecular Fiber Organization Regulation Of Cytoskeleton Organization Regulation Of Actin Filament-based Process Positive Regulation Of Supramolecular Fiber Organization Anchoring Junction Actin Filament-based Process Regulation Of Organelle Organization Positive Regulation Of Actin Filament Polymerization Focal Adhesion Positive Regulation Of Cytoskeleton Organization Regulation Of Plasma Membrane Bounded Cell Projection Organization Regulation Of Actin Filament Polymerization Cell Projection Organization Regulation Of Cell Projection Organization Positive Regulation Of Organelle Organization Actin Cytoskeleton Organization Regulation Of Cell Projection Assembly Regulation Of Cellular Component Size Regulation Of Ruffle Assembly Filopodium Actin-based Cell Projection Actin Cytoskeleton Positive Regulation Of Protein Polymerization Regulation Of Protein-containing Complex Assembly Regulation Of Lamellipodium Assembly Regulation Of Stress Fiber Assembly SCAR Complex SH3 Domain Binding Negative Regulation Of Cellular Component Organization Cytoplasm Regulation Of Cellular Component Organization Regulation Of Lamellipodium Organization Postsynapse Cytoskeleton Organization Regulation Of Cell Motility Regulation Of Cell Shape Positive Regulation Of Actin Filament Bundle Assembly Regulation Of Locomotion Cell Projection Morphogenesis Regulation Of Anatomical Structure Morphogenesis	Actin Filament Organization Actin Binding Profilin Binding Lamellipodium Supramolecular Fiber Organization Cardiac Muscle Thin Filament Assembly Actin Polymerization Or Depolymerization Filopodium Stress Fiber SH3 Domain Binding Cytoskeleton Z Disc Focal Adhesion Regulation Of Actin Filament Length Actin Filament Binding Neuron Projection Guidance Axon Guidance Structural Constituent Of Muscle Regulation Of Cellular Component Size Positive Regulation Of Actin Filament Polymerization Sarcomere Actin Cytoskeleton Protein Homotetramerization Cytoskeletal Protein Binding Protein Autoubiquitination Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Protein Polymerization Regulation Of Actin Filament-based Process Protein Tetramerization Muscle Cell Development Cytoplasm Regulation Of Actin Filament Polymerization Neuron Projection Development Somatic Muscle Development Mesenchyme Migration Regulation Of Cytoskeleton Organization Regulation Of Actin Polymerization Or Depolymerization Postsynapse To Nucleus Signaling Pathway Extrinsic Component Of Postsynaptic Density Membrane Skeletal Muscle Thin Filament Assembly Cell Projection Negative Regulation Of Ruffle Assembly Actin Polymerization-dependent Cell Motility Positive Regulation Of Supramolecular Fiber Organization Negative Regulation Of Schwann Cell Proliferation Regulation Of CD8-positive, Alpha-beta T Cell Proliferation Positive Regulation Of Cytoskeleton Organization Striated Muscle Thin Filament Protein Homooligomerization Ribosome-associated Ubiquitin-dependent Protein Catabolic Process
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