NAXD and KRTAP10-6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		NAXD	KRTAP10-6
Description		NAD(P)HX dehydratase	keratin associated protein 10-6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix	Cytosol Intermediate Filament Keratin Filament
	Molecular Function	Nucleotide Binding Protein Binding ATP Binding Lyase Activity Hydro-lyase Activity ATP-dependent NAD(P)H-hydrate Dehydratase Activity	Protein Binding
	Biological Process	NAD+ Biosynthetic Process Via The Salvage Pathway Nicotinamide Nucleotide Metabolic Process Metabolite Repair
Pathways		Nicotinate metabolism	Keratinization
Drugs
Diseases
GWAS
Interacting Genes		14 interacting genes: KRT31 KRT34 KRTAP1-3 KRTAP10-3 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP5-9 NOTCH2NLA SGTA SGTB UBQLN1 UBQLN2	87 interacting genes: ADAMTSL3 AVPI1 CLK1 CLK4 DHX57 DKK2 FOXD4 HAND1 HHEX HOXB5 KIAA0040 KIF9 KRTAP10-1 KRTAP10-5 KRTAP4-11 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-9 KRTAP9-8 LCE1A LCE1B LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A MOBP MT1B NAA10 NAXD NKD1 NMU NOL12 NPDC1 PBXIP1 PIN1 RSPO2 SLC33A2 SNIP1 SPATA3 STRA6 VASN WT1 YTHDC1 ZBTB24 ZC3HAV1 ZIM2 ZNF114 ZNF138 ZNF155 ZNF169 ZNF221 ZNF239 ZNF264 ZNF280C ZNF302 ZNF319 ZNF418 ZNF440 ZNF479 ZNF490 ZNF543 ZNF563 ZNF595 ZNF600 ZNF669 ZNF672 ZNF679 ZNF696 ZNF774 ZNF776 ZNF792 ZNHIT1
Entrez ID		55739	386674
HPRD ID		07698	11192
Ensembl ID		ENSG00000213995	ENSG00000188155
Uniprot IDs		A0A7P0T9D8 Q8IW45	P60371
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Positive Regulation Of ERAD Pathway TRC Complex Regulation Of ERAD Pathway Positive Regulation Of Response To Endoplasmic Reticulum Stress Structural Constituent Of Skin Epidermis Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Cytosol Regulation Of Response To Endoplasmic Reticulum Stress ERAD Pathway Positive Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Epidermis Development Identical Protein Binding Protein Targeting To ER Establishment Of Protein Localization To Endoplasmic Reticulum Polyubiquitin Modification-dependent Protein Binding Positive Regulation Of Proteolysis Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Response To Endoplasmic Reticulum Stress Negative Regulation Of Store-operated Calcium Channel Activity Protein Targeting To Membrane Intermediate Filament Organization Negative Regulation Of G Protein-coupled Receptor Internalization Autophagosome Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Negative Regulation Of Toll-like Receptor 3 Signaling Pathway Autophagosome Assembly BAT3 Complex Binding Regulation Of Protein Catabolic Process Regulation Of Proteolysis Autophagosome Organization Negative Regulation Of Clathrin-dependent Endocytosis Negative Regulation Of ERAD Pathway Proteasomal Protein Catabolic Process	Keratinization Epidermis Development DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Intermediate Filament Tissue Development Zinc Ion Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA Binding Regulation Of Transcription By RNA Polymerase II Keratin Filament Hair Cycle Regulation Of DNA-templated Transcription Regulation Of RNA Metabolic Process Regulation Of RNA Biosynthetic Process Protein Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Gene Expression Positive Regulation Of Wnt Signaling Pathway Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Metal Ion Binding Diaphragm Development Cartilage Morphogenesis Regulation Of Macromolecule Metabolic Process
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