NAXD

Description		NAD(P)HX dehydratase
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix
	Molecular Function	Nucleotide Binding Protein Binding ATP Binding Lyase Activity Hydro-lyase Activity ATP-dependent NAD(P)H-hydrate Dehydratase Activity
	Biological Process	NAD+ Biosynthetic Process Via The Salvage Pathway Nicotinamide Nucleotide Metabolic Process Metabolite Repair
Pathways		Nicotinate metabolism
Drugs
Diseases
GWAS
Interacting Genes		14 interacting genes: KRT31 KRT34 KRTAP1-3 KRTAP10-3 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP5-9 NOTCH2NLA SGTA SGTB UBQLN1 UBQLN2
Entrez ID		55739
HPRD ID		07698
Ensembl ID		ENSG00000213995
Uniprot IDs		A0A7P0T9D8 Q8IW45
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Positive Regulation Of ERAD Pathway TRC Complex Regulation Of ERAD Pathway Positive Regulation Of Response To Endoplasmic Reticulum Stress Structural Constituent Of Skin Epidermis Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Cytosol Regulation Of Response To Endoplasmic Reticulum Stress ERAD Pathway Positive Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Epidermis Development Identical Protein Binding Protein Targeting To ER Establishment Of Protein Localization To Endoplasmic Reticulum Polyubiquitin Modification-dependent Protein Binding Positive Regulation Of Proteolysis Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Response To Endoplasmic Reticulum Stress Negative Regulation Of Store-operated Calcium Channel Activity Protein Targeting To Membrane Intermediate Filament Organization Negative Regulation Of G Protein-coupled Receptor Internalization Autophagosome Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Negative Regulation Of Toll-like Receptor 3 Signaling Pathway Autophagosome Assembly BAT3 Complex Binding Regulation Of Protein Catabolic Process Regulation Of Proteolysis Autophagosome Organization Negative Regulation Of Clathrin-dependent Endocytosis Negative Regulation Of ERAD Pathway Proteasomal Protein Catabolic Process
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