LMBR1L and LCN1

Number of citations of the paper that reports this interaction (PubMedID 11287427)
0

Data Source:
HPRD (in vitro)

		LMBR1L	LCN1
Description		limb development membrane protein 1 like	lipocalin 1
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Membrane	Extracellular Region Extracellular Space
	Molecular Function	Transmembrane Signaling Receptor Activity Protein Binding	Cysteine-type Endopeptidase Inhibitor Activity Signaling Receptor Binding Protein Binding Zinc Ion Binding Chloride Ion Binding Small Molecule Binding
	Biological Process	Endocytosis Receptor-mediated Endocytosis Signal Transduction Wnt Signaling Pathway T Cell Differentiation T Cell Proliferation Hematopoietic Stem Cell Differentiation T Cell Apoptotic Process Negative Regulation Of Canonical Wnt Signaling Pathway	Proteolysis Sensory Perception Of Taste
Pathways			Transport of fatty acids
Drugs			Tretinoin
Diseases
GWAS		Bipolar disorder ( 31043756) Body size at age 10 ( 32376654) Brain morphology (MOSTest) ( 32665545)	Subcutaneous adipose tissue ( 29178545) Subcutaneous adipose tissue (sex interaction) ( 29178545)
Interacting Genes		5 interacting genes: CFTR CREB3 LCN1 MAGEA11 SCGB1A1	9 interacting genes: ALOX5 FAM25A FAM25C FAM25G LMBR1L LTF LYZ RECK UBQLN2
Entrez ID		55716	3933
HPRD ID		17276	01059
Ensembl ID		ENSG00000139636	ENSG00000160349
Uniprot IDs		A0A024R0Y9 A0A0S2Z6E3 Q6UX01	P31025
PDB IDs			1XKI 3EYC 4QAF 5T43
Enriched GO Terms of Interacting Partners?		Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Polychlorinated Biphenyl Binding Positive Regulation Of Deacetylase Activity Positive Regulation Of Anion Channel Activity Positive Regulation Of Enamel Mineralization Positive Regulation Of Monoatomic Anion Transport Positive Regulation Of Monoatomic Ion Transport Response To Ozone Response To Silicon Dioxide Response To Endoplasmic Reticulum Stress Positive Regulation Of Tooth Mineralization Chloride Channel Inhibitor Activity Transepithelial Water Transport Chloride Channel Regulator Activity Regulation Of Enamel Mineralization Membrane Hyperpolarization Negative Regulation Of Interleukin-13 Production Negative Regulation Of Interleukin-4 Production Phospholipase A2 Inhibitor Activity CCR1 Chemokine Receptor Binding Release From Viral Latency Bicarbonate Transmembrane Transporter Activity Intracellular PH Elevation Negative Regulation Of Interleukin-5 Production Amelogenesis ATPase-coupled Inorganic Anion Transmembrane Transporter Activity CAMP Response Element Binding Protein Binding Chloride Ion Binding Regulation Of Monoatomic Anion Transport Epithelial Fluid Transport Golgi-associated Vesicle Membrane Cellular Response To Forskolin Nuclear Body Induction Of Positive Chemotaxis	Leukotriene A4 Metabolic Process Regulation Of Response To Endoplasmic Reticulum Stress Leukotriene Production Involved In Inflammatory Response Leukotriene A4 Biosynthetic Process Regulation Of Bone Mineralization Arachidonate 5-lipoxygenase Activity Humoral Immune Response Arachidonate 8(S)-lipoxygenase Activity Positive Regulation Of Ossification Positive Regulation Of Bone Mineralization Positive Regulation Of Biomineral Tissue Development Specific Granule Lumen Negative Regulation Of Single-species Biofilm Formation In Or On Host Organism Tertiary Granule Lumen Defense Response To Gram-negative Bacterium Negative Regulation Of Tumor Necrosis Factor (ligand) Superfamily Member 11 Production Negative Regulation Of G Protein-coupled Receptor Internalization Regulation Of Ossification Arachidonate Metabolite Production Involved In Inflammatory Response Lipoxin Biosynthetic Process Arachidonate 12(S)-lipoxygenase Activity Iron Ion Binding Positive Regulation Of Leukocyte Adhesion To Arterial Endothelial Cell Oxidoreductase Activity, Acting On Single Donors With Incorporation Of Molecular Oxygen Phagocytic Vesicle Lumen Defense Response To Gram-positive Bacterium Positive Regulation Of Bone Mineralization Involved In Bone Maturation Killing Of Cells Of Another Organism Membrane Destabilizing Activity Regulation Of Establishment Of Blood-brain Barrier Negative Regulation Of Clathrin-dependent Endocytosis Regulation Of Leukocyte Adhesion To Arterial Endothelial Cell Epoxide Metabolic Process Negative Regulation Of Osteoclast Development Antimicrobial Humoral Response Negative Regulation Of Vascular Wound Healing Lysozyme Activity Blood Vessel Maturation Leukocyte Chemotaxis Involved In Inflammatory Response Cell Killing Positive Regulation Of Chondrocyte Proliferation Regulation Of Osteoclast Development
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