LCN1

Description		lipocalin 1
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space
	Molecular Function	Cysteine-type Endopeptidase Inhibitor Activity Signaling Receptor Binding Protein Binding Zinc Ion Binding Chloride Ion Binding Small Molecule Binding
	Biological Process	Proteolysis Sensory Perception Of Taste
Pathways		Transport of fatty acids
Drugs		Tretinoin
Diseases
GWAS		Subcutaneous adipose tissue ( 29178545) Subcutaneous adipose tissue (sex interaction) ( 29178545)
Interacting Genes		9 interacting genes: ALOX5 FAM25A FAM25C FAM25G LMBR1L LTF LYZ RECK UBQLN2
Entrez ID		3933
HPRD ID		01059
Ensembl ID		ENSG00000160349
Uniprot IDs		P31025
PDB IDs		1XKI 3EYC 4QAF 5T43
Enriched GO Terms of Interacting Partners?		Leukotriene A4 Metabolic Process Regulation Of Response To Endoplasmic Reticulum Stress Leukotriene Production Involved In Inflammatory Response Leukotriene A4 Biosynthetic Process Regulation Of Bone Mineralization Arachidonate 5-lipoxygenase Activity Humoral Immune Response Arachidonate 8(S)-lipoxygenase Activity Positive Regulation Of Ossification Positive Regulation Of Bone Mineralization Positive Regulation Of Biomineral Tissue Development Specific Granule Lumen Negative Regulation Of Single-species Biofilm Formation In Or On Host Organism Tertiary Granule Lumen Defense Response To Gram-negative Bacterium Negative Regulation Of Tumor Necrosis Factor (ligand) Superfamily Member 11 Production Negative Regulation Of G Protein-coupled Receptor Internalization Regulation Of Ossification Arachidonate Metabolite Production Involved In Inflammatory Response Lipoxin Biosynthetic Process Arachidonate 12(S)-lipoxygenase Activity Iron Ion Binding Positive Regulation Of Leukocyte Adhesion To Arterial Endothelial Cell Oxidoreductase Activity, Acting On Single Donors With Incorporation Of Molecular Oxygen Phagocytic Vesicle Lumen Defense Response To Gram-positive Bacterium Positive Regulation Of Bone Mineralization Involved In Bone Maturation Killing Of Cells Of Another Organism Membrane Destabilizing Activity Regulation Of Establishment Of Blood-brain Barrier Negative Regulation Of Clathrin-dependent Endocytosis Regulation Of Leukocyte Adhesion To Arterial Endothelial Cell Epoxide Metabolic Process Negative Regulation Of Osteoclast Development Antimicrobial Humoral Response Negative Regulation Of Vascular Wound Healing Lysozyme Activity Blood Vessel Maturation Leukocyte Chemotaxis Involved In Inflammatory Response Cell Killing Positive Regulation Of Chondrocyte Proliferation Regulation Of Osteoclast Development
Tagcloud ?