LCN1

Gene Name		lipocalin 1
Image
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space Extracellular Vesicular Exosome
	Molecular Function	Cysteine-type Endopeptidase Inhibitor Activity
	Biological Process	Retina Homeostasis Proteolysis Negative Regulation Of Endopeptidase Activity Long-chain Fatty Acid Transport Response To Stimulus Sensory Perception Of Taste Transmembrane Transport
Pathways		Transport of vitamins, nucleosides, and related molecules SLC-mediated transmembrane transport Transport of fatty acids Orphan transporters
Drugs
Diseases
GWAS
Protein-protein Interactions		3 interactors: LMBR1L LTF LYZ
Entrez ID		3933
HPRD ID		01059
Ensembl ID		ENSG00000160349
Uniprot IDs		P31025
PDB IDs		1XKI 3EYC
Enriched GO Terms of Interacting Partners?		Retina Homeostasis Iron Assimilation By Chelation And Transport Negative Regulation Of Tumor Necrosis Factor (ligand) Superfamily Member 11 Production Tissue Homeostasis Defense Response To Bacterium Negative Regulation Of Single-species Biofilm Formation In Or On Host Organism Negative Regulation Of Osteoclast Development Antifungal Humoral Response Positive Regulation Of Bone Mineralization Involved In Bone Maturation Positive Regulation Of Chondrocyte Proliferation Multicellular Organismal Homeostasis Positive Regulation Of Toll-like Receptor 4 Signaling Pathway Response To Host Immune Response Regulation Of Osteoclast Development Negative Regulation Of Lipopolysaccharide-mediated Signaling Pathway Response To Bacterium Positive Regulation Of Osteoblast Proliferation Positive Regulation Of Toll-like Receptor Signaling Pathway Innate Immune Response In Mucosa Regulation Of Lipopolysaccharide-mediated Signaling Pathway Response To Other Organism Response To Biotic Stimulus Regulation Of Osteoblast Proliferation Cytolysis Antibacterial Humoral Response Defense Response To Fungus Antimicrobial Humoral Response Negative Regulation Of Osteoclast Differentiation Mucosal Immune Response Response To Fungus Regulation Of Toll-like Receptor Signaling Pathway Positive Regulation Of Bone Mineralization Negative Regulation Of Tumor Necrosis Factor Superfamily Cytokine Production Positive Regulation Of Biomineral Tissue Development Phagosome Maturation Negative Regulation Of Myeloid Leukocyte Differentiation Regulation Of Osteoclast Differentiation Regulation Of Bone Mineralization Defense Response Positive Regulation Of Osteoblast Differentiation Homeostatic Process Iron Ion Transport Cellular Iron Ion Homeostasis Negative Regulation Of Myeloid Cell Differentiation Regulation Of Tumor Necrosis Factor Production Positive Regulation Of Ossification Interaction With Host Regulation Of Myeloid Leukocyte Differentiation Iron Ion Homeostasis Bone Morphogenesis
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