LCN1 and FAM25G

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		LCN1	FAM25G
Description		lipocalin 1	family with sequence similarity 25 member G
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space
	Molecular Function	Cysteine-type Endopeptidase Inhibitor Activity Signaling Receptor Binding Protein Binding Zinc Ion Binding Chloride Ion Binding Small Molecule Binding
	Biological Process	Proteolysis Sensory Perception Of Taste
Pathways		Transport of fatty acids
Drugs		Tretinoin
Diseases
GWAS		Subcutaneous adipose tissue ( 29178545) Subcutaneous adipose tissue (sex interaction) ( 29178545)
Interacting Genes		9 interacting genes: ALOX5 FAM25A FAM25C FAM25G LMBR1L LTF LYZ RECK UBQLN2	18 interacting genes: ARMC10 ARMCX3 COX16 GPD1 IGLL1 KLHL35 LCN1 LCN2 MIEF1 MIEF2 PPIC PPIF S100A6 SNX1 TDRKH TOMM20L TTPA ZFAND3
Entrez ID		3933	100133093
HPRD ID		01059	19458
Ensembl ID		ENSG00000160349	ENSG00000189090
Uniprot IDs		P31025	B3EWG3 B3EWG5 B3EWG6
PDB IDs		1XKI 3EYC 4QAF 5T43
Enriched GO Terms of Interacting Partners?		Leukotriene A4 Metabolic Process Regulation Of Response To Endoplasmic Reticulum Stress Leukotriene Production Involved In Inflammatory Response Leukotriene A4 Biosynthetic Process Regulation Of Bone Mineralization Arachidonate 5-lipoxygenase Activity Humoral Immune Response Arachidonate 8(S)-lipoxygenase Activity Positive Regulation Of Ossification Positive Regulation Of Bone Mineralization Positive Regulation Of Biomineral Tissue Development Specific Granule Lumen Negative Regulation Of Single-species Biofilm Formation In Or On Host Organism Tertiary Granule Lumen Defense Response To Gram-negative Bacterium Negative Regulation Of Tumor Necrosis Factor (ligand) Superfamily Member 11 Production Negative Regulation Of G Protein-coupled Receptor Internalization Regulation Of Ossification Arachidonate Metabolite Production Involved In Inflammatory Response Lipoxin Biosynthetic Process Arachidonate 12(S)-lipoxygenase Activity Iron Ion Binding Positive Regulation Of Leukocyte Adhesion To Arterial Endothelial Cell Oxidoreductase Activity, Acting On Single Donors With Incorporation Of Molecular Oxygen Phagocytic Vesicle Lumen Defense Response To Gram-positive Bacterium Positive Regulation Of Bone Mineralization Involved In Bone Maturation Killing Of Cells Of Another Organism Membrane Destabilizing Activity Regulation Of Establishment Of Blood-brain Barrier Negative Regulation Of Clathrin-dependent Endocytosis Regulation Of Leukocyte Adhesion To Arterial Endothelial Cell Epoxide Metabolic Process Negative Regulation Of Osteoclast Development Antimicrobial Humoral Response Negative Regulation Of Vascular Wound Healing Lysozyme Activity Blood Vessel Maturation Leukocyte Chemotaxis Involved In Inflammatory Response Cell Killing Positive Regulation Of Chondrocyte Proliferation Regulation Of Osteoclast Development	Mitochondrial Outer Membrane Cyclosporin A Binding Regulation Of Mitochondrion Organization Mitochondrion Mitochondrion Organization Positive Regulation Of Mitochondrial Fission Mitochondrial Fusion Small Molecule Binding Positive Regulation Of Protein Targeting To Membrane Regulation Of Mitochondrial Fission Regulation Of Protein Targeting To Membrane Peptidyl-prolyl Cis-trans Isomerase Activity Glycerol-3-phosphate Dehydrogenase (NAD+) Activity Positive Regulation Of Hippocampal Neuron Apoptotic Process Negative Regulation Of Establishment Of Blood-brain Barrier Regulation Of Proton-transporting ATPase Activity, Rotational Mechanism Glycerol-3-phosphate Dehydrogenase [NAD(P)+] Activity Glycerol-3-phosphate Catabolic Process Glycerol-3-phosphate Shuttle Positive Regulation Of Iron Ion Import Across Plasma Membrane Enterobactin Binding Positive Regulation Of Endothelial Tube Morphogenesis Iron Ion Sequestering Activity Positive Regulation Of Growth Rate TRNA Import Into Mitochondrion Cellular Response To Hydrogen Peroxide
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