SLC48A1 and LDAF1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SLC48A1	LDAF1
Description		solute carrier family 48 member 1	lipid droplet assembly factor 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Lysosome Lysosomal Membrane Endosome Plasma Membrane Endosome Membrane Membrane Phagocytic Vesicle Membrane Cytoplasmic Vesicle Endolysosome Phagolysosome Membrane	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Droplet Membrane
	Molecular Function	Protein Binding Heme Transmembrane Transporter Activity Heme Binding	Protein Binding
	Biological Process	Phagocytosis Lysosomal Transport Heme Transport Erythrocyte Differentiation Heme Metabolic Process Localization Of Cell Heme Export Heme Export From Vacuole To Cytoplasm	Lipid Droplet Formation
Pathways
Drugs
Diseases
GWAS		Asthma (adult onset) ( 31036433) Bipolar disorder ( 31043756) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494)
Interacting Genes		9 interacting genes: APP COMT FXR1 LAMP1 LDAF1 MEOX2 SHANK3 TMEM14B UNC93A	9 interacting genes: CACFD1 COQ8A GAD2 S100B SEC22A SLC48A1 SYT16 TMEM19 ZNF391
Entrez ID		55652	57146
HPRD ID		07916	17428
Ensembl ID		ENSG00000211584	ENSG00000011638
Uniprot IDs		Q6P1K1	I3L288 I3NI23 Q96B96
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Long-term Synaptic Potentiation Regulation Of Neuronal Synaptic Plasticity Positive Regulation Of Long-term Neuronal Synaptic Plasticity Associative Learning Negative Regulation Of Long-term Synaptic Potentiation Memory Positive Regulation Of Long-term Synaptic Potentiation Learning Response To Catecholamine Dendritic Spine Positive Regulation Of Excitatory Postsynaptic Potential Regulation Of Synaptic Plasticity Neuron Projection Organization Modulation Of Excitatory Postsynaptic Potential Learning Or Memory Amyloid-beta Complex Growth Cone Lamellipodium Cognition Visual Behavior Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Visual Learning Norepinephrine Secretion Catechol O-methyltransferase Activity Neuron Projection Regulation Of Synaptic Transmission, Glutamatergic Synapse Acetylcholine Receptor Activator Activity Axon Lipoprotein Particle Positive Regulation Of Protein Import Cellular Response To Phosphate Starvation Guanylate Kinase-associated Protein Clustering PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Dendrite Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Neuromuscular Process Phagolysosome Membrane Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Positive Regulation Of Synapse Structural Plasticity Striatal Medium Spiny Neuron Differentiation
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