LDAF1 and ZNF391

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		LDAF1	ZNF391
Description		lipid droplet assembly factor 1	zinc finger protein 391
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Droplet Membrane	Nucleus
	Molecular Function	Protein Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Lipid Droplet Formation	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS			Aspartate aminotransferase levels ( 33547301) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Feeling nervous ( 29500382) Fish- and plant-related diet ( 32066663) Liver iron content ( 34128465) Refractive error ( 32231278) Serum alkaline phosphatase levels ( 33547301) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		9 interacting genes: CACFD1 COQ8A GAD2 S100B SEC22A SLC48A1 SYT16 TMEM19 ZNF391	5 interacting genes: AGTRAP ARL6IP1 CMTM5 LDAF1 RTN3
Entrez ID		57146	346157
HPRD ID		17428	18893
Ensembl ID		ENSG00000011638	ENSG00000124613
Uniprot IDs		I3L288 I3NI23 Q96B96	Q9UJN7
PDB IDs
Enriched GO Terms of Interacting Partners?			Endoplasmic Reticulum Tubular Network Membrane Organization Endoplasmic Reticulum Tubular Network Formation Endoplasmic Reticulum Membrane Organization Endoplasmic Reticulum Tubular Network Organization Endoplasmic Reticulum Membrane Endoplasmic Reticulum Organization Endoplasmic Reticulum Positive Regulation Of L-glutamate Import Across Plasma Membrane Angiotensin Type II Receptor Activity Regulation Of Endoplasmic Reticulum Tubular Network Organization Sec61 Translocon Complex Regulation Of L-glutamate Import Across Plasma Membrane Cotranslational Protein Targeting To Membrane Lipid Droplet Formation Endoplasmic Reticulum Tubular Network Positive Regulation Of Amino Acid Transport Angiotensin-activated Signaling Pathway Negative Regulation Of Amyloid-beta Formation Negative Regulation Of Amyloid Precursor Protein Catabolic Process Negative Regulation Of Myoblast Differentiation
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