IRF2BPL

Description		interferon regulatory factor 2 binding protein like
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GO Annotations	Cellular Component	Extracellular Space Nucleus Nucleoplasm
	Molecular Function	Protein Binding Zinc Ion Binding Transferase Activity Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Nervous System Development Protein Ubiquitination Positive Regulation Of Transcription By RNA Polymerase II Development Of Secondary Female Sexual Characteristics
Pathways
Drugs
Diseases
GWAS		Adverse response to lamotrigine and phenytoin ( 22379998) Alanine aminotransferase levels ( 33547301 34315874) Aspartate aminotransferase levels ( 33547301 34315874) Atrial fibrillation ( 29892015 30061737) Feeling nervous ( 29500382) Paclitaxel disposition in epithelial ovarian cancer ( 29367611)
Novel Interacting Genes		1 novel interacting genes: FGFR3
Interacting Genes		3 interacting genes: HCK TSG101 UBE2Q1
Entrez ID		64207
HPRD ID		10713
Ensembl ID		ENSG00000119669
Uniprot IDs		Q9H1B7
PDB IDs		2CS3
Enriched GO Terms of Interacting Partners?		Regulation Of Peptidyl-tyrosine Phosphorylation Secretion By Cell Secretion Transport Vesicle Fibroblast Growth Factor Receptor Apoptotic Signaling Pathway Positive Regulation Of Phospholipase Activity Bone Maturation Protein Tyrosine Kinase Activity Respiratory Burst After Phagocytosis Leukocyte Migration Involved In Immune Response Exocytosis Exosomal Secretion Positive Regulation Of Ubiquitin-dependent Endocytosis Positive Regulation Of Viral Budding Via Host ESCRT Complex Prolactin Secretion Fibroblast Growth Factor Receptor Activity Regulation Of Organelle Assembly Regulation Of Extracellular Exosome Assembly ATP Binding Endochondral Bone Growth Positive Regulation Of Lipase Activity Respiratory Burst Involved In Defense Response Regulation Of Endocytosis Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity Virion Binding Suckling Behavior ESCRT I Complex Nucleotide Binding Chondrocyte Proliferation Regulation Of Protein Phosphorylation Focal Adhesion Regulation Of Cell Population Proliferation Regulation Of Phosphorylation Transferase Activity Type II Interferon-mediated Signaling Pathway Regulation Of Podosome Assembly Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Negative Regulation Of Signaling Receptor Activity Negative Regulation Of Protein Tyrosine Kinase Activity Positive Regulation Of Exosomal Secretion Bone Growth Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Fibroblast Growth Factor Binding Protein Kinase Activity Positive Regulation Of Cellular Component Biogenesis Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Respiratory Burst Negative Regulation Of Peptidyl-tyrosine Phosphorylation Regulation Of Exosomal Secretion Viral Budding Via Host ESCRT Complex
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