FEM1A and ACAA1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FEM1A	ACAA1
Description		fem-1 homolog A	acetyl-CoA acyltransferase 1
Image		No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Cytoplasm Mitochondrion Cytosol Cul2-RING Ubiquitin Ligase Complex	Extracellular Region Peroxisome Peroxisomal Matrix Cytosol Membrane Specific Granule Lumen
	Molecular Function	Protein Binding EP4 Subtype Prostaglandin E2 Receptor Binding Molecular Adaptor Activity Ubiquitin-like Ligase-substrate Adaptor Activity	Acetyl-CoA C-acetyltransferase Activity Acetyl-CoA C-acyltransferase Activity Protein Binding Acetate CoA-transferase Activity Transferase Activity Acyltransferase Activity Acyltransferase Activity, Transferring Groups Other Than Amino-acyl Groups Acetyl-CoA C-myristoyltransferase Activity Long-chain Fatty Acyl-CoA Oxidase Activity
	Biological Process	MAPK Cascade Protein Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Inflammatory Response Positive Regulation Of Inflammatory Response Regulation Of Ubiquitin-protein Transferase Activity Ubiquitin-dependent Protein Catabolic Process Via The C-end Degron Rule Pathway	Very Long-chain Fatty Acid Metabolic Process Lipid Metabolic Process Fatty Acid Metabolic Process Fatty Acid Beta-oxidation Bile Acid Metabolic Process Phenylacetate Catabolic Process Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase Alpha-linolenic Acid Metabolic Process
Pathways		Neddylation	alpha-linolenic acid (ALA) metabolism Beta-oxidation of very long chain fatty acids Neutrophil degranulation Peroxisomal protein import Peroxisomal protein import TYSND1 cleaves peroxisomal proteins
Drugs
Diseases
GWAS		Height ( 31562340)	Gut microbiota (bacterial taxa) ( 27723756)
Interacting Genes		11 interacting genes: ACAA1 GOLGA6L9 INCA1 KIFC3 MALT1 MYOM3 NDUFAB1 OGFOD1 PPM1F PTGER4 WWOX	4 interacting genes: FEM1A HAT1 TFCP2 TXNDC11
Entrez ID		55527	30
HPRD ID		16888	06815
Ensembl ID		ENSG00000141965	ENSG00000060971
Uniprot IDs		Q9BSK4	A0A024R2M6 A0A140VJX0 P09110
PDB IDs			2IIK
Enriched GO Terms of Interacting Partners?			EP4 Subtype Prostaglandin E2 Receptor Binding
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