YOD1 and ZFP57

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		YOD1	ZFP57
Description		YOD1 deubiquitinase	ZFP57 zinc finger protein
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol	Nucleus
	Molecular Function	Catalytic Activity Cysteine-type Deubiquitinase Activity Protein Binding Peptidase Activity Cysteine-type Peptidase Activity Zinc Ion Binding Hydrolase Activity Ubiquitin Protein Ligase Binding Metal Ion Binding K63-linked Deubiquitinase Activity Deubiquitinase Activity K48-linked Deubiquitinase Activity	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Proteolysis Response To Unfolded Protein Macroautophagy Endoplasmic Reticulum Unfolded Protein Response Protein K29-linked Deubiquitination Protein K11-linked Deubiquitination ERAD Pathway Protein K63-linked Deubiquitination Protein K48-linked Deubiquitination Negative Regulation Of Retrograde Protein Transport, ER To Cytosol Protein K27-linked Deubiquitination Protein K33-linked Deubiquitination	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Autosome Genomic Imprinting
Pathways		Ovarian tumor domain proteases
Drugs
Diseases			Transient neonatal diabetes mellitus (TNDM)
GWAS		Systolic blood pressure ( 28234671)	Albumin-globulin ratio ( 29403010) Autism spectrum disorder or schizophrenia ( 28540026) Hip circumference adjusted for BMI ( 34021172) Offspring birth weight ( 31043758) Sepsis (hospital admission) ( 32592749) White matter integrity (mean diffusivity) ( 32358547)
Interacting Genes		30 interacting genes: ATG14 BIRC3 DAZAP2 DDIT4L FAM168A INCA1 LMO2 MKRN1 NEDD4 NGRN PLEKHB2 PSMA7 RFC2 RIPK1 RNF216 SHARPIN SNCA SPART TP53BP2 TRAF6 TRIM54 TRIM55 TRIM63 TRIM8 UBC UBE3A UBXN6 USP15 USP21 ZFP57	9 interacting genes: CFTR CIB3 DVL3 EMD KANK2 MKRN3 MLH1 POLR1C YOD1
Entrez ID		55432	346171
HPRD ID		10312	19560
Ensembl ID		ENSG00000180667	ENSG00000204644
Uniprot IDs		Q5VVQ6	A0A1U9X8V5 A0A7I2S1M6 B7ZW61 Q9NU63
PDB IDs		4BOQ 4BOS 4BOZ
Enriched GO Terms of Interacting Partners?		Ubiquitin Protein Ligase Activity Post-translational Protein Modification Protein Polyubiquitination Canonical NF-kappaB Signal Transduction Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein Modification Process Positive Regulation Of Canonical NF-kappaB Signal Transduction Ubiquitin-protein Transferase Activity Protein Metabolic Process Protein K63-linked Ubiquitination Regulation Of Canonical NF-kappaB Signal Transduction Protein-containing Complex Protein K48-linked Ubiquitination Zinc Ion Binding Cytoplasm Positive Regulation Of Intracellular Signal Transduction Innate Immune Response Positive Regulation Of Cell Communication Positive Regulation Of Signaling Transcription Coactivator Activity Identical Protein Binding Proteolysis Proteolysis Involved In Protein Catabolic Process Tumor Necrosis Factor-mediated Signaling Pathway Progesterone Receptor Signaling Pathway Positive Regulation Of Signal Transduction Nucleus Defense Response To Symbiont Defense Response To Other Organism Response To External Biotic Stimulus Positive Regulation Of Protein Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Regulation Of Primary Metabolic Process Macromolecule Catabolic Process Modification-dependent Protein Catabolic Process Defense Response Response To Interleukin-1 Regulation Of Phosphorus Metabolic Process Nuclear Body Positive Regulation Of Protein Modification Process Regulation Of Defense Response Transferase Activity Negative Regulation Of Necroptotic Process Response To Other Organism Regulation Of RIG-I Signaling Pathway Negative Regulation Of Programmed Necrotic Cell Death Protein Catabolic Process Positive Regulation Of Execution Phase Of Apoptosis Regulation Of Protein Modification Process	Positive Regulation Of Anion Channel Activity Regulation Of Protein Localization Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding TMEM240-body Meiotic Spindle Midzone Assembly Meiotic Metaphase Chromosome Alignment Chiasma Late Recombination Nodule Meiotic Metaphase I Homologous Chromosome Alignment Negative Regulation Of Vitamin D Receptor Signaling Pathway Regulation Of Establishment Of Protein Localization Regulation Of Cellular Localization Positive Regulation Of Enamel Mineralization Regulation Of Protein Transport Positive Regulation Of Monoatomic Anion Transport Guanine/thymine Mispair Binding Male Meiosis Chromosome Segregation MutLalpha Complex Negative Regulation Of Mitotic Recombination Protein K29-linked Deubiquitination Protein K27-linked Deubiquitination Transepithelial Water Transport Regulation Of Intracellular Protein Transport Homologous Chromosome Segregation Female Meiosis Chromosome Segregation Mismatch Repair Complex Protein K33-linked Deubiquitination
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