HEMGN and ZBTB1

Number of citations of the paper that reports this interaction (PubMedID 24740910)
0

Data Source:
BioGRID (two hybrid)

		HEMGN	ZBTB1
Description		hemogen	zinc finger and BTB domain containing 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Nucleus Nucleoplasm Nuclear Body Nuclear Membrane
	Molecular Function	Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Protein Homodimerization Activity Metal Ion Binding Protein Heterodimerization Activity K63-linked Polyubiquitin Modification-dependent Protein Binding
	Biological Process	Cell Differentiation Regulation Of Osteoblast Differentiation	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Cytokine Production Immune System Process Regulation Of Immune System Process Positive Regulation Of T Cell Mediated Immunity DNA Repair Chromatin Remodeling DNA Damage Response Translesion Synthesis Cell Differentiation B Cell Differentiation Positive Regulation Of Natural Killer Cell Differentiation T Cell Differentiation In Thymus Cellular Response To UV MRNA Transcription By RNA Polymerase II Innate Immune Response Positive Regulation Of T Cell Differentiation Thymus Development Protein Homooligomerization Positive Regulation Of Pro-T Cell Differentiation
Pathways
Drugs
Diseases
GWAS		Alopecia areata ( 25608926) Platelet count ( 27863252) Platelet distribution width ( 27863252) Plateletcrit ( 27863252) Quantitative traits ( 19197348) Thyroid cancer (Papillary, radiation-related) ( 20350937)	Lymphocyte count ( 32888494) Neutrophil percentage of white cells ( 32888494) Urinary albumin-to-creatinine ratio ( 31630189)
Interacting Genes		34 interacting genes: AURKA AXIN2 BCL10 BUB1 CDH1 CTBP1 CTBP2 DCC DLC1 EGFR ENO1 EP300 FBXW7 FLCN GATA1 H2AC6 HMGA1 HSPA1A KAT6A KRAS MCC MED17 MLH3 NRAS ODC1 PTPRJ SMAD4 SP100 SRC THAP11 TLR2 TRAF3 WHRN ZBTB1	22 interacting genes: AKR7A2 AR EWSR1 FAM161A FANCG HEMGN KAT5 LZTR1 MAML3 MFAP1 NDN PCNA PIH1D2 PIM1 SCNM1 TRAF1 TRIM42 UBC UBE2I ZBTB25 ZNF417 ZNF572
Entrez ID		55363	22890
HPRD ID		17100	15688
Ensembl ID		ENSG00000136929	ENSG00000126804
Uniprot IDs		Q9BXL5	Q9Y2K1
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Gene Expression Negative Regulation Of Cell Population Proliferation Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Metabolic Process Regulation Of Cell Communication Regulation Of Signaling Regulation Of Cell Population Proliferation Negative Regulation Of Macromolecule Metabolic Process Regulation Of Protein Metabolic Process Regulation Of Multicellular Organismal Process Regulation Of Signal Transduction Regulation Of Metabolic Process Regulation Of RNA Metabolic Process Transcription Coregulator Binding Negative Regulation Of Metabolic Process Negative Regulation Of RNA Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Apoptotic Process Regulation Of Cell Development Regulation Of Programmed Cell Death Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Intracellular Signal Transduction Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Primary Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Regulation Of Protein Catabolic Process Positive Regulation Of RNA Metabolic Process Regulation Of Cell Differentiation Negative Regulation Of Cellular Component Organization Regulation Of Developmental Process Regulation Of Apoptotic Signaling Pathway Negative Regulation Of Cell Growth Developmental Process Positive Regulation Of Intracellular Signal Transduction Hemopoiesis Transcription Coactivator Activity	Nucleoplasm Regulation Of DNA-templated Transcription Negative Regulation Of DNA-templated Transcription Negative Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Biosynthetic Process Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of RNA Metabolic Process Zinc Ion Binding Regulation Of RNA Metabolic Process Transcription Factor Binding Negative Regulation Of Nucleobase-containing Compound Metabolic Process
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